Detailed information of TA system TA281603

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2561052..2561495
• Replicon: chromosome
• Accession: NZ_CP124900
• Organism: Enterococcus faecalis strain EfsC108

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ58_RS12205
• Protein ID: WP_023894767.1
• Coordinates: 2561052..2561156 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2561296..2561495 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ58_RS12190	2556343..2557056	-	714	WP_002354877.1	trehalose operon repressor	-
QLQ58_RS12195	2557318..2560062	+	2745	WP_282897134.1	glycosyl hydrolase family 65 protein	-
QLQ58_RS12200	2560077..2560727	+	651	WP_002354875.1	beta-phosphoglucomutase	-
QLQ58_RS12205	2561052..2561156	-	105	WP_023894767.1	putative holin-like toxin	Toxin
-	2561296..2561495	+	200	-	-	Antitoxin
QLQ58_RS12210	2561428..2561571	-	144	WP_282897135.1	type I toxin-antitoxin system toxin PepG1	-
QLQ58_RS12215	2561805..2562776	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
QLQ58_RS12220	2562951..2563388	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
QLQ58_RS12225	2563521..2564075	-	555	WP_282897136.1	Maf family protein	-
QLQ58_RS12230	2564100..2566232	-	2133	WP_282897137.1	DNA mismatch repair endonuclease MutL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3799.63 Da
• Isoelectric Point: 10.0079

>T281603 WP_023894767.1 NZ_CP124900:c2561156-2561052 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 200 bp

>AT281603 NZ_CP124900:2561296-2561495 [Enterococcus faecalis]
TTTTTAGGGAATTGTGCTATAATGAAAACGAAAAGAGAGATATGCGTCAACATACCTCTCTGATGTAGAGCCGTTTAAGA
CGGTGACTTTTTGAATTATTTAAAAATAACCGTACTCGGTCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAAGCAAT
TTCACAATCAGTGCAATCAAAGCAATGGTAAATATACCAA

Structures

Antitoxin