Detailed information of TA system TA281597

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2486923..2487148
• Replicon: chromosome
• Accession: NZ_CP124900
• Organism: Enterococcus faecalis strain EfsC108

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ58_RS11855
• Protein ID: WP_021164442.1
• Coordinates: 2487047..2487148 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2486923..2487110 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ58_RS11830	2482543..2483496	-	954	WP_085443718.1	siderophore ABC transporter substrate-binding protein	-
QLQ58_RS11835	2483535..2484290	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ58_RS11840	2484287..2485252	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ58_RS11845	2485249..2486196	-	948	WP_002394759.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ58_RS11850	2486381..2486833	+	453	WP_282897119.1	YueI family protein	-
QLQ58_RS11855	2487047..2487148	-	102	WP_021164442.1	putative holin-like toxin	Toxin
QLQ58_RS11860	2487339..2489609	-	2271	WP_002368430.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ58_RS11865	2489780..2490280	+	501	WP_153853912.1	cysteine hydrolase family protein	-
QLQ58_RS11870	2490886..2491782	+	897	WP_002365354.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3625.38 Da
• Isoelectric Point: 4.5869

>T281597 WP_021164442.1 NZ_CP124900:c2487148-2487047 [Enterococcus faecalis]
MSIEATLELMISFATLVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 188 bp

>AT281597 NZ_CP124900:2486923-2487110 [Enterococcus faecalis]
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAACGCAACAAGGGTTGCA

Structures

Antitoxin