Detailed information of TA system TA281588

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 66479..66693
• Replicon: plasmid p1_EfsC109-2_rep9b
• Accession: NZ_CP124899
• Organism: Enterococcus faecalis strain EfsC109-2

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: QLQ52_RS14455
• Protein ID: WP_002360667.1
• Coordinates: 66479..66589 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	66629..66693 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ52_RS14410	61664..61870	+	207	Protein_66	transposase	-
QLQ52_RS14415	62400..63020	+	621	WP_021732893.1	recombinase family protein	-
QLQ52_RS14420	63037..63324	+	288	WP_010708491.1	hypothetical protein	-
QLQ52_RS14425	63318..63542	+	225	WP_010708492.1	ultraviolet resistance protein UvrA repressor UvrC	-
QLQ52_RS14430	63603..63812	+	210	WP_002387638.1	hypothetical protein	-
QLQ52_RS14435	63974..64126	+	153	WP_225850000.1	DUF6440 family protein	-
QLQ52_RS14440	64553..65881	+	1329	WP_021732894.1	ultraviolet resistance protein UvrA	-
QLQ52_RS14445	65878..66228	+	351	WP_002399364.1	hypothetical protein	-
QLQ52_RS14450	66185..66397	+	213	WP_002360669.1	hypothetical protein	-
QLQ52_RS14455	66479..66589	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
-	66629..66693	-	65	-	-	Antitoxin
QLQ52_RS14460	66829..67125	+	297	WP_002360665.1	replication control protein PrgN	-
QLQ52_RS14465	67379..68161	+	783	WP_002360664.1	ParA family protein	-
QLQ52_RS14470	68154..68510	+	357	WP_002360663.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Mobilizable plasmid	-	prgB/asc10	1..68769	68769

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T281588 WP_002360667.1 NZ_CP124899:66479-66589 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 65 bp

>AT281588 NZ_CP124899:c66693-66629 [Enterococcus faecalis]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin