Detailed information of TA system TA281578

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 400708..400932
• Replicon: chromosome
• Accession: NZ_CP124898
• Organism: Enterococcus faecalis strain EfsC109-2

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ52_RS01880
• Protein ID: WP_224561205.1
• Coordinates: 400708..400809 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	400754..400932 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ52_RS01860	396035..396433	+	399	WP_002354951.1	glyoxalase	-
QLQ52_RS01865	396484..397380	-	897	WP_002365354.1	YitT family protein	-
QLQ52_RS01870	397570..398076	-	507	WP_002378810.1	cysteine hydrolase family protein	-
QLQ52_RS01875	398247..400517	+	2271	WP_002378809.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ52_RS01880	400708..400809	+	102	WP_224561205.1	putative holin-like toxin	Toxin
-	400754..400932	-	179	-	-	Antitoxin
QLQ52_RS01885	400995..401447	-	453	WP_002378807.1	YueI family protein	-
QLQ52_RS01890	401632..402579	+	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ52_RS01895	402576..403541	+	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ52_RS01900	403538..404293	+	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ52_RS01905	404332..405285	+	954	WP_002359060.1	siderophore ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3629.37 Da
• Isoelectric Point: 4.5869

>T281578 WP_224561205.1 NZ_CP124898:400708-400809 [Enterococcus faecalis]
MSIEATLELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 179 bp

>AT281578 NZ_CP124898:c400932-400754 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCCTTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTT
TTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCG
AAAATCAGTAGTGCAACAA

Structures

Antitoxin