Detailed information of TA system TA281571

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-ratA/Fst(toxin)
• Location: 39615..39856
• Replicon: plasmid p2_EfsC116_rep9a
• Accession: NZ_CP124896
• Organism: Enterococcus faecalis strain EfsC116

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: QLQ63_RS15070
• Protein ID: WP_002360667.1
• Coordinates: 39615..39725 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	39765..39856 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ63_RS15050 (37205)	37205..37810	+	606	WP_000238804.1	recombinase family protein	-
QLQ63_RS15055 (37857)	37857..39017	+	1161	WP_267594822.1	Y-family DNA polymerase	-
QLQ63_RS15060 (39014)	39014..39364	+	351	WP_002400993.1	hypothetical protein	-
QLQ63_RS15065 (39321)	39321..39533	+	213	WP_002360669.1	hypothetical protein	-
QLQ63_RS15070 (39615)	39615..39725	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (39765)	39765..39856	-	92	NuclAT_0	-	Antitoxin
- (39765)	39765..39856	-	92	NuclAT_0	-	Antitoxin
- (39765)	39765..39856	-	92	NuclAT_0	-	Antitoxin
- (39765)	39765..39856	-	92	NuclAT_0	-	Antitoxin
QLQ63_RS15075 (39965)	39965..40255	+	291	WP_049084802.1	hypothetical protein	-
QLQ63_RS15080 (40359)	40359..40730	-	372	WP_000049959.1	replication-associated protein RepC	-
QLQ63_RS15085 (40723)	40723..41568	-	846	WP_000239313.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	cylR2 / cylL / cylS / cylM / cylB / cylA / cylI	1..42039	42039

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T281571 WP_002360667.1 NZ_CP124896:39615-39725 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 92 bp

>AT281571 NZ_CP124896:c39856-39765 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin