Detailed information of TA system TA281549

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2655205..2655465
• Replicon: chromosome
• Accession: NZ_CP124894
• Organism: Enterococcus faecalis strain EfsC116

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ63_RS13030
• Protein ID: WP_075551663.1
• Coordinates: 2655364..2655465 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2655205..2655415 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ63_RS13005 (2650889)	2650889..2651842	-	954	WP_002394760.1	siderophore ABC transporter substrate-binding protein	-
QLQ63_RS13010 (2651881)	2651881..2652636	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ63_RS13015 (2652633)	2652633..2653598	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ63_RS13020 (2653595)	2653595..2654542	-	948	WP_002359058.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ63_RS13025 (2654727)	2654727..2655179	+	453	WP_002359057.1	YueI family protein	-
- (2655205)	2655205..2655415	+	211	NuclAT_4	-	Antitoxin
- (2655242)	2655242..2655419	+	178	NuclAT_12	-	-
QLQ63_RS13030 (2655364)	2655364..2655465	-	102	WP_075551663.1	putative holin-like toxin	Toxin
QLQ63_RS13035 (2655654)	2655654..2657924	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ63_RS13040 (2658095)	2658095..2658595	+	501	WP_010709949.1	cysteine hydrolase family protein	-
QLQ63_RS13045 (2658898)	2658898..2659794	+	897	WP_002354953.1	YitT family protein	-
QLQ63_RS13050 (2659845)	2659845..2660243	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281549 WP_075551663.1 NZ_CP124894:c2655465-2655364 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 211 bp

>AT281549 NZ_CP124894:2655205-2655415 [Enterococcus faecalis]
TTCCATTTATAATAGAATTATGCTATTATGAAAATGAAAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAACA
CCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGT
TATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin