281546

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 567876..568108 Replicon chromosome
Accession NZ_CP124894
Organism Enterococcus faecalis strain EfsC116

Toxin (Protein)


Gene name txpA Uniprot ID C7CXQ5
Locus tag QLQ63_RS02855 Protein ID WP_002355568.1
Coordinates 567876..567992 (+) Length 39 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 567903..568108 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ63_RS02845 (563314) 563314..565572 + 2259 WP_002363179.1 DNA helicase PcrA -
QLQ63_RS02850 (565698) 565698..567728 + 2031 WP_010710796.1 NAD-dependent DNA ligase LigA -
QLQ63_RS02855 (567876) 567876..567992 + 117 WP_002355568.1 putative holin-like toxin Toxin
- (567903) 567903..568108 - 206 NuclAT_3 - Antitoxin
QLQ63_RS02860 (568310) 568310..568615 + 306 WP_002355569.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC -
QLQ63_RS02865 (568615) 568615..570084 + 1470 WP_033593283.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
QLQ63_RS02870 (570084) 570084..571514 + 1431 WP_002358703.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
QLQ63_RS02875 (571533) 571533..572621 + 1089 WP_002355572.1 diacylglycerol kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(3-35)


Sequences

Toxin        


Download         Length: 39 a.a.        Molecular weight: 4065.93 Da        Isoelectric Point: 5.9482

>T281546 WP_002355568.1 NZ_CP124894:567876-567992 [Enterococcus faecalis]
MFLSVEAALGLMIGFATLVVTIIFGILALVLDNKNNRS

Download         Length: 117 bp

Antitoxin


Download         Length: 206 bp

>AT281546 NZ_CP124894:c568108-567903 [Enterococcus faecalis]
AAAAGAGAGATATGCAGGAACATACCTCTCTAGTAGCCACTACTAGTTATAAGAACTAGCGGCTTACTGAGTTATTGGTT
TTATTTCAAACGCTTAACCGTTCAGCTCCTCAAAGCTTATGAACGGTTATTTTTGTTGTCTAAGACAAGCGCTAAGATAC
CGAAGATAATGGTCACAACAAGTGTTGCAAAACCAATCATCAGTCC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B4XLM6

Antitoxin

Download structure file

References