Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2736479..2736816 Replicon chromosome
Accession NZ_CP124890
Organism Enterococcus faecalis strain EfsPF2

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag QLQ38_RS13020 Protein ID WP_002396786.1
Coordinates 2736479..2736622 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2736554..2736816 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
- (2731509) 2731509..2731685 - 177 NuclAT_10 - -
- (2731543) 2731543..2731697 - 155 NuclAT_7 - -
QLQ38_RS13010 (2731832) 2731832..2731936 + 105 WP_021164545.1 putative holin-like toxin -
- (2731869) 2731869..2732124 - 256 NuclAT_3 - -
QLQ38_RS13015 (2732126) 2732126..2735884 - 3759 WP_010824298.1 WxL domain-containing protein -
- (2736235) 2736235..2736368 - 134 NuclAT_11 - -
- (2736225) 2736225..2736382 - 158 NuclAT_5 - -
QLQ38_RS13020 (2736479) 2736479..2736622 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2736766) 2736766..2736815 + 50 NuclAT_15 - -
- (2736554) 2736554..2736816 - 263 NuclAT_9 - Antitoxin
QLQ38_RS13025 (2736816) 2736816..2739875 - 3060 WP_048949307.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T281515 WP_002396786.1 NZ_CP124890:2736479-2736622 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 263 bp

>AT281515 NZ_CP124890:c2736816-2736554 [Enterococcus faecalis]
AAATAAAAATGCCCGAGCCTCTTATTTTTCTAAGGCTCGGGCATTTTTATTGATGGTCTTTTGATGGTCGTTGTGCTATA
ATAGCATTGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTAGCGATTTTTAGTGATT
TATAAAAAATAACCGTGCTCGCTAAAGTTGACGGTTATTTTTTATTGTCTTCTTTAACAGCCTCTAGGATTCCGAAGATT
AACGTTGCGATAAAAGAACCGAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References