Detailed information of TA system TA281508

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2731543..2731936
• Replicon: chromosome
• Accession: NZ_CP124890
• Organism: Enterococcus faecalis strain EfsPF2

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ38_RS13010
• Protein ID: WP_021164545.1
• Coordinates: 2731832..2731936 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2731543..2731697 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ38_RS12990 (2726686)	2726686..2726901	-	216	WP_002354768.1	zinc ribbon domain-containing protein	-
QLQ38_RS12995 (2727040)	2727040..2728032	+	993	WP_048949306.1	biotin--[acetyl-CoA-carboxylase] ligase	-
QLQ38_RS13000 (2728296)	2728296..2728934	-	639	WP_002375448.1	lytic polysaccharide monooxygenase	-
QLQ38_RS13005 (2729619)	2729619..2731235	+	1617	WP_010824297.1	phosphatase PAP2/LCP family protein	-
- (2731308)	2731308..2731395	-	88	NuclAT_14	-	-
- (2731509)	2731509..2731685	-	177	NuclAT_10	-	-
- (2731543)	2731543..2731697	-	155	NuclAT_7	-	Antitoxin
QLQ38_RS13010 (2731832)	2731832..2731936	+	105	WP_021164545.1	putative holin-like toxin	Toxin
- (2731869)	2731869..2732124	-	256	NuclAT_3	-	-
QLQ38_RS13015 (2732126)	2732126..2735884	-	3759	WP_010824298.1	WxL domain-containing protein	-
- (2736235)	2736235..2736368	-	134	NuclAT_11	-	-
- (2736225)	2736225..2736382	-	158	NuclAT_5	-	-
QLQ38_RS13020 (2736479)	2736479..2736622	+	144	WP_002396786.1	putative holin-like toxin	-
- (2736766)	2736766..2736815	+	50	NuclAT_15	-	-
- (2736554)	2736554..2736816	-	263	NuclAT_9	-	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3813.70 Da
• Isoelectric Point: 10.3686

>T281508 WP_021164545.1 NZ_CP124890:2731832-2731936 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 155 bp

>AT281508 NZ_CP124890:c2731697-2731543 [Enterococcus faecalis]
TTTTTAGGAAAGTGTGCTATAATAATAATGAAAAGAGAGGTATGCGCCAACATACCTCTCTAGTGTAGAGCGGTTTAAGA
CGGTGACCTTTTGGATTATTTAAAAATAACCGTACTTGGTCAAAGTAGACGGTTATTTTTTCTTGTCTTCTTTAA

Structures

Antitoxin