Detailed information of TA system TA281502

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2629427..2629651
• Replicon: chromosome
• Accession: NZ_CP124890
• Organism: Enterococcus faecalis strain EfsPF2

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ38_RS12540
• Protein ID: WP_023894767.1
• Coordinates: 2629547..2629651 (-)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2629427..2629614 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ38_RS12525 (2624843)	2624843..2627587	+	2745	WP_048949538.1	glycosyl hydrolase family 65 protein	-
QLQ38_RS12530 (2627602)	2627602..2628252	+	651	WP_002419627.1	beta-phosphoglucomutase	-
- (2628321)	2628321..2628437	+	117	NuclAT_13	-	-
QLQ38_RS12535 (2628713)	2628713..2629306	+	594	WP_048949539.1	PBECR4 domain-containing protein	-
- (2629427)	2629427..2629614	+	188	NuclAT_4	-	Antitoxin
QLQ38_RS12540 (2629547)	2629547..2629651	-	105	WP_023894767.1	putative holin-like toxin	Toxin
- (2629803)	2629803..2629944	+	142	NuclAT_6	-	-
- (2629803)	2629803..2629946	+	144	NuclAT_12	-	-
QLQ38_RS12545 (2630034)	2630034..2630159	-	126	WP_002383214.1	hypothetical protein	-
QLQ38_RS12550 (2630443)	2630443..2630976	+	534	WP_002385180.1	CPBP family intramembrane metalloprotease	-
QLQ38_RS12555 (2631030)	2631030..2632001	-	972	WP_002381060.1	ribose-phosphate diphosphokinase	-
QLQ38_RS12560 (2632176)	2632176..2632613	-	438	WP_002354871.1	peptide-methionine (R)-S-oxide reductase MsrB	-
QLQ38_RS12565 (2632746)	2632746..2633300	-	555	WP_002354869.1	Maf family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-34)

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3799.63 Da
• Isoelectric Point: 10.0079

>T281502 WP_023894767.1 NZ_CP124890:c2629651-2629547 [Enterococcus faecalis]
MSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Nucleotide

• Length: 105 bp

Antitoxin

Nucleotide

• Length: 188 bp

>AT281502 NZ_CP124890:2629427-2629614 [Enterococcus faecalis]
TGTGCTATAATGAAAATGAAAAGAGAGATATGCTTCAACATACCTCTCTGATGTTGAGCCGTTTAAGACGGTGACTTTTT
GAATTATTTAAAAATAACCGTACTCGGTCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAAGCAATTTCACAATCAGC
GCAATCAAAGCAATGGTAAACATACCAA

Structures

Antitoxin