Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 360535..360798 Replicon chromosome
Accession NZ_CP124889
Organism Enterococcus faecalis strain EfsPF5

Toxin (Protein)


Gene name txpA Uniprot ID S4BYM2
Locus tag QLQ34_RS01715 Protein ID WP_002392696.1
Coordinates 360535..360678 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 360611..360798 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ34_RS01690 356862..357416 + 555 WP_002354869.1 Maf family protein -
QLQ34_RS01695 357549..357986 + 438 WP_002354871.1 peptide-methionine (R)-S-oxide reductase MsrB -
QLQ34_RS01700 358161..359132 + 972 WP_002381060.1 ribose-phosphate diphosphokinase -
QLQ34_RS01705 359186..359461 - 276 WP_224805966.1 CPBP family intramembrane metalloprotease -
QLQ34_RS01710 360002..360127 + 126 WP_002398921.1 hypothetical protein -
QLQ34_RS01715 360535..360678 + 144 WP_002392696.1 type I toxin-antitoxin system toxin PepG1 Toxin
- 360611..360798 - 188 - - Antitoxin
QLQ34_RS01720 361048..361698 - 651 WP_002354875.1 beta-phosphoglucomutase -
QLQ34_RS01725 361713..364457 - 2745 WP_002398920.1 glycosyl hydrolase family 65 protein -
QLQ34_RS01730 364719..365432 + 714 WP_002381063.1 trehalose operon repressor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5297.43 Da        Isoelectric Point: 10.6867

>T281493 WP_002392696.1 NZ_CP124889:360535-360678 [Enterococcus faecalis]
MSVLPKFTERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 188 bp

>AT281493 NZ_CP124889:c360798-360611 [Enterococcus faecalis]
TGTGCTATAATGAAAATGAAAAGAGAGATATGCTTCAACATACCTCTCTGATGTAGAGCCGTTTAAGACGGTGACTTTTT
GAATTATTTAAAAATAACCGTACTCGGTCAAAGTTGACGGTTATTTTTTATTGTCATTTTTAAGCAATTTCACAATCAGT
GCAATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S4BYM2

Antitoxin

Download structure file

References