Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 275841..276167 Replicon chromosome
Accession NZ_CP124889
Organism Enterococcus faecalis strain EfsPF5

Toxin (Protein)


Gene name txpA Uniprot ID A0A3N3Z2N6
Locus tag QLQ34_RS01310 Protein ID WP_073340360.1
Coordinates 275841..275981 (-) Length 47 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 275983..276167 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ34_RS01305 275469..275612 - 144 WP_002381035.1 putative holin-like toxin -
QLQ34_RS01310 275841..275981 - 141 WP_073340360.1 putative holin-like toxin Toxin
- 275983..276167 + 185 - - Antitoxin
QLQ34_RS01315 276100..276243 - 144 WP_002392818.1 type I toxin-antitoxin system toxin PepG1 -
QLQ34_RS01320 276573..278189 - 1617 WP_002381036.1 phosphatase PAP2/LCP family protein -
QLQ34_RS01325 278882..279511 + 630 WP_002354763.1 lytic polysaccharide monooxygenase -
QLQ34_RS01330 279775..280767 - 993 WP_002354765.1 biotin--[acetyl-CoA-carboxylase] ligase -
QLQ34_RS01335 280906..281121 + 216 WP_002354768.1 zinc ribbon domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-46)


Sequences

Toxin        


Download         Length: 47 a.a.        Molecular weight: 5218.33 Da        Isoelectric Point: 10.3265

>T281485 WP_073340360.1 NZ_CP124889:c275981-275841 [Enterococcus faecalis]
ISLKNTNKNIVYCTTYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 141 bp

Antitoxin


Download         Length: 185 bp

>AT281485 NZ_CP124889:275983-276167 [Enterococcus faecalis]
TGCTACAATAGAGACGAAAAGAGAGGTATGCTCTAACATACCTCTCTAGTGTAGAGCCGTTTAAGACGGTGACCTTTTTA
GTTACAAAAAATAACCGTACTCAGTCAAAGTAGACGGTTATTTTTTCTTGTCATTTTTAAGCAATTTCACAATCAGCGCA
ATCAAAGCAATGGTAAACATACCAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3N3Z2N6

Antitoxin

Download structure file

References