Detailed information of TA system TA281467

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2601185..2601663
• Replicon: chromosome
• Accession: NZ_CP124887
• Organism: Enterococcus faecalis strain EfsPNK7

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ46_RS12425
• Protein ID: WP_162780856.1
• Coordinates: 2601185..2601286 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2601462..2601663 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ46_RS12400	2596680..2597633	-	954	WP_010713727.1	siderophore ABC transporter substrate-binding protein	-
QLQ46_RS12405	2597672..2598427	-	756	WP_282859008.1	ATP-binding cassette domain-containing protein	-
QLQ46_RS12410	2598424..2599389	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ46_RS12415	2599386..2600333	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ46_RS12420	2600518..2600970	+	453	WP_010707017.1	YueI family protein	-
QLQ46_RS12425	2601185..2601286	-	102	WP_162780856.1	putative holin-like toxin	Toxin
-	2601462..2601663	+	202	-	-	Antitoxin
QLQ46_RS12430	2601617..2601718	-	102	WP_224800345.1	putative holin-like toxin	-
QLQ46_RS12435	2601907..2604177	-	2271	WP_010713724.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ46_RS12440	2604348..2604848	+	501	WP_002408270.1	cysteine hydrolase family protein	-
QLQ46_RS12445	2605549..2606445	+	897	WP_002354953.1	YitT family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3624.40 Da
• Isoelectric Point: 6.0656

>T281467 WP_162780856.1 NZ_CP124887:c2601286-2601185 [Enterococcus faecalis]
MSIEATLELMISFATLVALLIFGILEATKNNKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 202 bp

>AT281467 NZ_CP124887:2601462-2601663 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTTATACCAACA
CCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTGAATCTTAACCGTTCGGCCTACGAAGCTTGTGAACGGTTATT
TTTTATTGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTA

Structures

Antitoxin