Detailed information of TA system TA281437

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2585593..2585816
• Replicon: chromosome
• Accession: NZ_CP124886
• Organism: Enterococcus faecalis strain EfsPF13

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ55_RS12645
• Protein ID: WP_075551663.1
• Coordinates: 2585715..2585816 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2585593..2585770 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ55_RS12620	2581240..2582193	-	954	WP_002354964.1	siderophore ABC transporter substrate-binding protein	-
QLQ55_RS12625	2582232..2582987	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ55_RS12630	2582984..2583949	-	966	WP_002354961.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ55_RS12635	2583946..2584893	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ55_RS12640	2585078..2585530	+	453	WP_002354958.1	YueI family protein	-
-	2585593..2585770	+	178	-	-	Antitoxin
QLQ55_RS12645	2585715..2585816	-	102	WP_075551663.1	putative holin-like toxin	Toxin
QLQ55_RS12650	2586148..2586249	-	102	WP_075551663.1	putative holin-like toxin	-
QLQ55_RS12655	2586439..2588709	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ55_RS12660	2588880..2589380	+	501	WP_002354954.1	cysteine hydrolase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281437 WP_075551663.1 NZ_CP124886:c2585816-2585715 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 178 bp

>AT281437 NZ_CP124886:2585593-2585770 [Enterococcus faecalis]
AAAAGAGAGGTATGCGGGTACATACCTCTCTTTTATACCAGCGCCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTT
TTATTACTGTTTAACCGTTCGGCCTGTCAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGA
AAATCAGTAGTGCAACAA

Structures

Antitoxin