Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-ratA/-
Location 2779654..2779990 Replicon chromosome
Accession NZ_CP124884
Organism Enterococcus faecalis strain EfsPF15

Toxin (Protein)


Gene name txpA Uniprot ID A0A1J6YG70
Locus tag QLQ47_RS13290 Protein ID WP_002396786.1
Coordinates 2779654..2779797 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name ratA
Locus tag -
Coordinates 2779941..2779990 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QLQ47_RS13270 (2774771) 2774771..2774986 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
QLQ47_RS13275 (2775125) 2775125..2776117 + 993 WP_023894581.1 biotin--[acetyl-CoA-carboxylase] ligase -
QLQ47_RS13280 (2776381) 2776381..2777019 - 639 WP_002378863.1 lytic polysaccharide monooxygenase -
QLQ47_RS13285 (2777705) 2777705..2779321 + 1617 WP_047648929.1 phosphatase PAP2/LCP family protein -
QLQ47_RS13290 (2779654) 2779654..2779797 + 144 WP_002396786.1 putative holin-like toxin Toxin
- (2779941) 2779941..2779990 + 50 NuclAT_14 - Antitoxin
- (2779729) 2779729..2779991 - 263 NuclAT_11 - -
QLQ47_RS13295 (2779992) 2779992..2784683 - 4692 WP_282851328.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5203.19 Da        Isoelectric Point: 8.6626

>T281428 WP_002396786.1 NZ_CP124884:2779654-2779797 [Enterococcus faecalis]
MNVSTKIYERRGLLSIAEALALMISFGSFIATLIFGILEAVKEDNKK

Download         Length: 144 bp

Antitoxin


Download         Length: 50 bp

>AT281428 NZ_CP124884:2779941-2779990 [Enterococcus faecalis]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1J6YG70

Antitoxin

Download structure file

References