Detailed information of TA system TA281416

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2629023..2629248
• Replicon: chromosome
• Accession: NZ_CP124884
• Organism: Enterococcus faecalis strain EfsPF15

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ47_RS12610
• Protein ID: WP_075551663.1
• Coordinates: 2629147..2629248 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2629023..2629202 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ47_RS12580 (2624239)	2624239..2625192	-	954	WP_002394760.1	siderophore ABC transporter substrate-binding protein	-
QLQ47_RS12585 (2625231)	2625231..2625986	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ47_RS12590 (2625983)	2625983..2626948	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ47_RS12595 (2626945)	2626945..2627892	-	948	WP_002359058.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ47_RS12600 (2628077)	2628077..2628529	+	453	WP_002359057.1	YueI family protein	-
- (2628555)	2628555..2628765	+	211	NuclAT_6	-	-
- (2628592)	2628592..2628769	+	178	NuclAT_5	-	-
QLQ47_RS12605 (2628714)	2628714..2628815	-	102	WP_075551663.1	putative holin-like toxin	-
- (2628989)	2628989..2629198	+	210	NuclAT_7	-	-
- (2629023)	2629023..2629202	+	180	NuclAT_4	-	Antitoxin
QLQ47_RS12610 (2629147)	2629147..2629248	-	102	WP_075551663.1	putative holin-like toxin	Toxin
QLQ47_RS12615 (2629438)	2629438..2631708	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ47_RS12620 (2631879)	2631879..2632379	+	501	WP_010709949.1	cysteine hydrolase family protein	-
QLQ47_RS12625 (2632682)	2632682..2633578	+	897	WP_002354953.1	YitT family protein	-
QLQ47_RS12630 (2633629)	2633629..2634027	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281416 WP_075551663.1 NZ_CP124884:c2629248-2629147 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 180 bp

>AT281416 NZ_CP124884:2629023-2629202 [Enterococcus faecalis]
TGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACACCAGTTATAAGAACTGGTGGCTTACTGAGTTAAGT
TTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTTATTTTTTATCGTTTTTCGTTGCTTCAAGGATACC
GAAAATCAGTAGTGCAACAA

Structures

Antitoxin