Detailed information of TA system TA281404

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 51025..51266
• Replicon: plasmid p1_EfsPF20_rep9a
• Accession: NZ_CP124883
• Organism: Enterococcus faecalis strain EfsPF20

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: QLQ60_RS14645
• Protein ID: WP_002360667.1
• Coordinates: 51025..51135 (+)
• Length: 37 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	51175..51266 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ60_RS14600 (46223)	46223..47384	-	1162	Protein_49	IS3 family transposase	-
QLQ60_RS14605 (47458)	47458..47565	+	108	Protein_50	recombinase family protein	-
QLQ60_RS14610 (47555)	47555..47869	+	315	WP_002383634.1	hypothetical protein	-
QLQ60_RS14615 (47863)	47863..48087	+	225	WP_002383635.1	ultraviolet resistance protein UvrA repressor UvrC	-
QLQ60_RS14620 (48148)	48148..48357	+	210	WP_002382045.1	hypothetical protein	-
QLQ60_RS14625 (48369)	48369..48671	+	303	WP_002372577.1	DUF6440 family protein	-
QLQ60_RS14630 (49099)	49099..50427	+	1329	WP_002400994.1	ultraviolet resistance protein UvrA	-
QLQ60_RS14635 (50424)	50424..50774	+	351	WP_002400993.1	hypothetical protein	-
QLQ60_RS14640 (50731)	50731..50943	+	213	WP_002360669.1	hypothetical protein	-
QLQ60_RS14645 (51025)	51025..51135	+	111	WP_002360667.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (51175)	51175..51266	-	92	NuclAT_0	-	Antitoxin
- (51175)	51175..51266	-	92	NuclAT_0	-	Antitoxin
- (51175)	51175..51266	-	92	NuclAT_0	-	Antitoxin
- (51175)	51175..51266	-	92	NuclAT_0	-	Antitoxin
QLQ60_RS14650 (51375)	51375..51665	+	291	WP_001137528.1	hypothetical protein	-
QLQ60_RS14655 (51769)	51769..52140	-	372	WP_000049959.1	replication-associated protein RepC	-
QLQ60_RS14660 (52133)	52133..52978	-	846	WP_000239313.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..53449	53449
	-	flank	IS/Tn	-	-	46223..47059	836

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 37 a.a.
• Molecular weight: 4117.92 Da
• Isoelectric Point: 4.1672

>T281404 WP_002360667.1 NZ_CP124883:51025-51135 [Enterococcus faecalis]
VLFVKDLMSLVIAPIFVGLVLEMISRVLDEEDDNRK

Nucleotide

• Length: 111 bp

Antitoxin

Nucleotide

• Length: 92 bp

>AT281404 NZ_CP124883:c51266-51175 [Enterococcus faecalis]
TAAAAATATGTTATACTAAAGGTGCGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin