Detailed information of TA system TA281393

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): txpA-ratA/-
• Location: 2691745..2692229
• Replicon: chromosome
• Accession: NZ_CP124882
• Organism: Enterococcus faecalis strain EfsPF20

Toxin (Protein)

• Gene name: txpA
• Uniprot ID: -
• Locus tag: QLQ60_RS13115
• Protein ID: WP_075551663.1
• Coordinates: 2691745..2691846 (-)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	2692020..2692229 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QLQ60_RS13090	2687270..2688223	-	954	WP_002365350.1	siderophore ABC transporter substrate-binding protein	-
QLQ60_RS13095	2688262..2689017	-	756	WP_002354962.1	ATP-binding cassette domain-containing protein	-
QLQ60_RS13100	2689014..2689979	-	966	WP_002371665.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ60_RS13105	2689976..2690923	-	948	WP_002354960.1	iron chelate uptake ABC transporter family permease subunit	-
QLQ60_RS13110	2691108..2691560	+	453	WP_002354958.1	YueI family protein	-
QLQ60_RS13115	2691745..2691846	-	102	WP_075551663.1	putative holin-like toxin	Toxin
-	2692020..2692229	+	210	-	-	Antitoxin
QLQ60_RS13120	2692178..2692279	-	102	WP_075551663.1	putative holin-like toxin	-
QLQ60_RS13125	2692469..2694739	-	2271	WP_002354955.1	bifunctional glutamate--cysteine ligase/glutathione synthetase	-
QLQ60_RS13130	2694910..2695410	+	501	WP_002365352.1	cysteine hydrolase family protein	-
QLQ60_RS13135	2695809..2696705	+	897	WP_002365354.1	YitT family protein	-
QLQ60_RS13140	2696756..2697154	-	399	WP_002354951.1	glyoxalase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-33)

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3599.34 Da
• Isoelectric Point: 4.5869

>T281393 WP_075551663.1 NZ_CP124882:c2691846-2691745 [Enterococcus faecalis]
MSIEAALELMISFAAFVALLIFGILEATKNDKK

Nucleotide

• Length: 102 bp

Antitoxin

Nucleotide

• Length: 210 bp

>AT281393 NZ_CP124882:2692020-2692229 [Enterococcus faecalis]
TTCCATTTTAAATAGAATTATGCTATTATGAAAATGAAAAGAGAGATATGCTACTACATACCTCTCCTTTATACCAACAC
CAGTTATAAGAACTGGTGGCTTACTGAGTTAAGTTTTTGTTGTTCTTTAACCGTTCAGCCGTCTAAGCTTATGAACGGTT
ATTTTTTATCGTTTTTCGTTGCTTCAAGGATACCGAAAATCAGTAGTGCA

Structures

Antitoxin