28137

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-RNAII/-
Location 2874845..2875181 Replicon chromosome
Accession NC_018221
Organism Enterococcus faecalis D32

Toxin (Protein)


Gene name txpA Uniprot ID -
Locus tag EFD32_RS14460 Protein ID WP_041161797.1
Coordinates 2874845..2874988 (+) Length 48 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 2875132..2875181 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD32_RS14435 2869967..2870182 - 216 WP_002354768.1 zinc ribbon domain-containing protein -
EFD32_RS14440 2870321..2871313 + 993 WP_002358973.1 biotin--[acetyl-CoA-carboxylase] ligase -
EFD32_RS14445 2871577..2872206 - 630 WP_002388632.1 lytic polysaccharide monooxygenase -
EFD32_RS14455 2872899..2874515 + 1617 WP_002372620.1 phosphatase PAP2/LCP family protein -
EFD32_RS14460 2874845..2874988 + 144 WP_041161797.1 putative holin-like toxin Toxin
- 2875132..2875181 + 50 - - Antitoxin
EFD32_RS14465 2875183..2879769 - 4587 WP_010730419.1 WxL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(14-47)


Sequences

Toxin        


Download         Length: 48 a.a.        Molecular weight: 5301.34 Da        Isoelectric Point: 10.4690

>T28137 WP_041161797.1 NC_018221:2874845-2874988 [Enterococcus faecalis D32]
MNVSTKIYERRGLLSIAEALALMISFRSFIATLIFGILEAVKENNKK

Download         Length: 144 bp

>T28137 NC_018221:2874845-2874988 [Enterococcus faecalis D32]
ATGAATGTAAGTACTAAAATCTATGAAAGGAGAGGCCTTTTGTCTATCGCAGAAGCTTTAGCTCTGATGATTAGTTTCCG
TTCTTTTATCGCAACGTTAATCTTCGGAATCCTAGAGGCTGTAAAAGAAAACAATAAAAAATAA

Antitoxin


Download         Length: 50 bp

>AT28137 NC_018221:2875132-2875181 [Enterococcus faecalis D32]
AATAAAAATGCCCGAGCCTTAGAAAAATAAGAGGCTCGGGCATTTTTATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References