Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) fst-RNAII/-
Location 1945711..1945952 Replicon chromosome
Accession NC_018221
Organism Enterococcus faecalis D32

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag EFD32_RS16340 Protein ID WP_172760012.1
Coordinates 1945815..1945952 (-) Length 46 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 1945711..1945775 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD32_RS09750 1941868..1943284 - 1417 Protein_1834 IS1182 family transposase -
EFD32_RS09765 1944864..1945229 - 366 Protein_1836 replication protein RepA -
EFD32_RS16510 1945413..1945577 + 165 WP_154231859.1 hypothetical protein -
- 1945711..1945775 + 65 - - Antitoxin
EFD32_RS16340 1945815..1945952 - 138 WP_172760012.1 type I toxin-antitoxin system Fst family toxin Toxin
EFD32_RS09780 1946245..1947000 - 756 WP_010709161.1 IS21-like element helper ATPase IstB -
EFD32_RS15915 1947013..1948231 - 1219 Protein_1840 IS21 family transposase -
EFD32_RS09800 1948541..1948768 + 228 Protein_1841 preprotein translocase subunit YajC -
EFD32_RS15920 1948752..1949027 - 276 WP_080019838.1 hypothetical protein -
EFD32_RS09805 1949361..1949701 + 341 Protein_1843 DUF3784 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1934074..1955102 21028
- inside IScluster/Tn - - 1942354..1951167 8813


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 4986.95 Da        Isoelectric Point: 4.4286

>T28127 WP_172760012.1 NC_018221:c1945952-1945815 [Enterococcus faecalis D32]
MRQLASIGGVLFVKDLMSLVIAPIFVGLVLELISRVLDEEDDSRK

Download         Length: 138 bp

>T28127 NC_018221:c1945952-1945815 [Enterococcus faecalis D32]
ATGCGGCAGCTCGCCTCGATTGGAGGTGTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGG
ATTGGTTCTGGAATTGATTTCTCGTGTGTTGGACGAGGAAGACGATAGCCGAAAGTAA

Antitoxin


Download         Length: 65 bp

>AT28127 NC_018221:1945711-1945775 [Enterococcus faecalis D32]
AACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGATTGCTTTTTTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References