Detailed information of TA system TA028126

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-ratA/-
• Location: 1945684..1945952
• Replicon: chromosome
• Accession: NC_018221
• Organism: Enterococcus faecalis D32

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: EFD32_RS16340
• Protein ID: WP_172760012.1
• Coordinates: 1945815..1945952 (-)
• Length: 46 a.a.

Antitoxin (RNA)

Gene name	ratA
Locus tag	-
Coordinates	1945684..1945775 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
EFD32_RS09750	1941868..1943284	-	1417	Protein_1834	IS1182 family transposase	-
EFD32_RS09765	1944864..1945229	-	366	Protein_1836	replication protein RepA	-
EFD32_RS16510	1945413..1945577	+	165	WP_154231859.1	hypothetical protein	-
-	1945684..1945775	+	92	NuclAT_3	-	Antitoxin
-	1945684..1945775	+	92	NuclAT_3	-	Antitoxin
-	1945684..1945775	+	92	NuclAT_3	-	Antitoxin
-	1945684..1945775	+	92	NuclAT_3	-	Antitoxin
EFD32_RS16340	1945815..1945952	-	138	WP_172760012.1	type I toxin-antitoxin system Fst family toxin	Toxin
EFD32_RS09780	1946245..1947000	-	756	WP_010709161.1	IS21-like element helper ATPase IstB	-
EFD32_RS15915	1947013..1948231	-	1219	Protein_1840	IS21 family transposase	-
EFD32_RS09800	1948541..1948768	+	228	Protein_1841	preprotein translocase subunit YajC	-
EFD32_RS15920	1948752..1949027	-	276	WP_080019838.1	hypothetical protein	-
EFD32_RS09805	1949361..1949701	+	341	Protein_1843	DUF3784 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1934074..1955102	21028
	-	inside	IScluster/Tn	-	-	1942354..1951167	8813

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 46 a.a.
• Molecular weight: 4986.95 Da
• Isoelectric Point: 4.4286

>T28126 WP_172760012.1 NC_018221:c1945952-1945815 [Enterococcus faecalis D32]
MRQLASIGGVLFVKDLMSLVIAPIFVGLVLELISRVLDEEDDSRK

Nucleotide

• Length: 138 bp

>T28126 NC_018221:c1945952-1945815 [Enterococcus faecalis D32]
ATGCGGCAGCTCGCCTCGATTGGAGGTGTGTTATTTGTGAAAGATTTAATGTCGTTGGTTATCGCACCGATCTTTGTAGG
ATTGGTTCTGGAATTGATTTCTCGTGTGTTGGACGAGGAAGACGATAGCCGAAAGTAA

Antitoxin

Nucleotide

• Length: 92 bp

>AT28126 NC_018221:1945684-1945775 [Enterococcus faecalis D32]
TAATAATATGTTACACTAAAGGTACGAAACGACATTAAATCGTACAAATAACACAAAAAGCAATCCTACGGCGAATAGGA
TTGCTTTTTTTT

Structures

Antitoxin