Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) fst-RNAII/-
Location 349332..349535 Replicon chromosome
Accession NC_018221
Organism Enterococcus faecalis D32

Toxin (Protein)


Gene name fst Uniprot ID -
Locus tag EFD32_RS01880 Protein ID WP_157734666.1
Coordinates 349431..349535 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 349332..349396 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD32_RS01865 344944..346692 + 1749 WP_002393697.1 PTS transporter subunit EIIC -
EFD32_RS01870 346683..348716 + 2034 WP_002361171.1 transcription antiterminator -
EFD32_RS01875 348727..349161 + 435 WP_002358391.1 PTS sugar transporter subunit IIA -
- 349332..349396 + 65 - - Antitoxin
EFD32_RS01880 349431..349535 - 105 WP_157734666.1 type I toxin-antitoxin system Fst family toxin Toxin
EFD32_RS01885 349772..351544 + 1773 WP_014862103.1 PTS mannitol transporter subunit IICBA -
EFD32_RS01890 351559..351996 + 438 WP_002355279.1 PTS sugar transporter subunit IIA -
EFD32_RS01895 352011..353165 + 1155 WP_002355280.1 mannitol-1-phosphate 5-dehydrogenase -
EFD32_RS01900 353232..354347 - 1116 WP_002380024.1 FAD-binding oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.



Sequences


Toxin        


Download         Length: 35 a.a.        Molecular weight: 4014.85 Da        Isoelectric Point: 6.4459

>T28122 WP_157734666.1 NC_018221:c349535-349431 [Enterococcus faecalis D32]
VHHIYEIVTKILVPIFVGIVLKLVTIWLEKQNEE

Download         Length: 105 bp

>T28122 NC_018221:c349535-349431 [Enterococcus faecalis D32]
GTGCATCACATATACGAGATTGTCACAAAAATTCTTGTGCCGATTTTTGTCGGGATTGTCCTGAAACTTGTAACCATTTG
GTTGGAAAAACAGAACGAGGAATAA

Antitoxin


Download         Length: 65 bp

>AT28122 NC_018221:349332-349396 [Enterococcus faecalis D32]
CTTGTGACAAAGTCGTGCATGGATGCACTAAAAAGACACCCTATTGTGGTAGGGTGTCTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References