Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5047602..5048256 Replicon chromosome
Accession NZ_CP124732
Organism Pseudomonas sp. GM17

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag PMI20_RS22430 Protein ID WP_007929614.1
Coordinates 5047602..5047952 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PMI20_RS22435 Protein ID WP_007929615.1
Coordinates 5047942..5048256 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PMI20_RS22420 (PMI20_022420) 5044353..5045885 + 1533 WP_007929612.1 NADH-quinone oxidoreductase subunit M -
PMI20_RS22425 (PMI20_022425) 5045893..5047356 + 1464 WP_007929613.1 NADH-quinone oxidoreductase subunit NuoN -
PMI20_RS22430 (PMI20_022430) 5047602..5047952 + 351 WP_007929614.1 hypothetical protein Toxin
PMI20_RS22435 (PMI20_022435) 5047942..5048256 + 315 WP_007929615.1 transcriptional regulator Antitoxin
PMI20_RS22440 (PMI20_022440) 5048428..5050170 - 1743 WP_007929616.1 ABC transporter substrate-binding protein -
PMI20_RS22445 (PMI20_022445) 5050221..5050493 - 273 WP_007929617.1 DUF2160 domain-containing protein -
PMI20_RS22450 (PMI20_022450) 5050504..5051304 - 801 WP_007929618.1 carbohydrate ABC transporter permease -
PMI20_RS22455 (PMI20_022455) 5051316..5052182 - 867 WP_007929620.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13763.74 Da        Isoelectric Point: 9.3412

>T281130 WP_007929614.1 NZ_CP124732:5047602-5047952 [Pseudomonas sp. GM17]
MDALFIELPPFQRYRQDYLDDELFRSLQLELLKAPEAGDLIEGTGGLRKIRFVDERRHKGKRGGIRVIYYWWSGGAQFWL
FTLYAKNEQSDLAPQQKKLLKQLLNREVEARTHHET

Download         Length: 351 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11850.76 Da        Isoelectric Point: 10.7886

>AT281130 WP_007929615.1 NZ_CP124732:5047942-5048256 [Pseudomonas sp. GM17]
MKRDIFSELVEGFDALAKERQGKLTLRSHKVKLSALLPITAEEVLAVREQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQATTLIRLVQRFPDTVERLAALA

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References