Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 3949063..3949321 Replicon chromosome
Accession NZ_CP124490
Organism Escherichia coli strain AVS0456

Toxin (Protein)


Gene name hokC Uniprot ID -
Locus tag QJP91_RS19105 Protein ID WP_000634316.1
Coordinates 3949187..3949321 (+) Length 45 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 3949063..3949120 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJP91_RS19090 3944892..3946151 - 1260 WP_000494928.1 hypothetical protein -
QJP91_RS19095 3946280..3947773 - 1494 WP_001173016.1 sulfatase-like hydrolase/transferase -
QJP91_RS19100 3947794..3948555 - 762 WP_001274833.1 outer membrane protein OmpK -
- 3949063..3949120 - 58 - - Antitoxin
QJP91_RS19105 3949187..3949321 + 135 WP_000634316.1 Hok/Gef family protein Toxin
QJP91_RS19110 3949425..3950555 - 1131 WP_001118464.1 molecular chaperone DnaJ -
QJP91_RS19115 3950644..3952560 - 1917 WP_000516135.1 molecular chaperone DnaK -
QJP91_RS19120 3952931..3953335 + 405 WP_000843689.1 DUF2541 family protein -
QJP91_RS19125 3953361..3954074 + 714 WP_001102393.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(1-41)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4777.67 Da        Isoelectric Point: 4.6979

>T280552 WP_000634316.1 NZ_CP124490:3949187-3949321 [Escherichia coli]
MIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 135 bp

Antitoxin


Download         Length: 58 bp

>AT280552 NZ_CP124490:c3949120-3949063 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References