Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 3079412..3079914 | Replicon | chromosome |
Accession | NZ_CP124481 | ||
Organism | Escherichia coli strain AVS0756 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | S1P977 |
Locus tag | QJP55_RS15195 | Protein ID | WP_000767822.1 |
Coordinates | 3079412..3079666 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | S1Q063 |
Locus tag | QJP55_RS15200 | Protein ID | WP_001259255.1 |
Coordinates | 3079663..3079914 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QJP55_RS15175 (3075905) | 3075905..3077263 | - | 1359 | WP_000019194.1 | putrescine/proton symporter PlaP | - |
QJP55_RS15180 (3077253) | 3077253..3077315 | - | 63 | WP_010723108.1 | membrane protein YoeI | - |
QJP55_RS15185 (3077530) | 3077530..3078459 | - | 930 | WP_000803366.1 | LysR substrate-binding domain-containing protein | - |
QJP55_RS15190 (3078505) | 3078505..3079329 | - | 825 | WP_000754737.1 | SDR family oxidoreductase | - |
QJP55_RS15195 (3079412) | 3079412..3079666 | - | 255 | WP_000767822.1 | type II toxin-antitoxin system mRNA interferase toxin YoeB | Toxin |
QJP55_RS15200 (3079663) | 3079663..3079914 | - | 252 | WP_001259255.1 | YoeB-YefM toxin-antitoxin system antitoxin YefM | Antitoxin |
QJP55_RS15205 (3080197) | 3080197..3080247 | + | 51 | WP_001364200.1 | his operon leader peptide | - |
QJP55_RS15210 (3080393) | 3080393..3081292 | + | 900 | WP_000131782.1 | ATP phosphoribosyltransferase | - |
QJP55_RS15215 (3081298) | 3081298..3082602 | + | 1305 | WP_001546022.1 | histidinol dehydrogenase | - |
QJP55_RS15220 (3082599) | 3082599..3083669 | + | 1071 | WP_000108941.1 | histidinol-phosphate transaminase | - |
QJP55_RS15225 (3083669) | 3083669..3084736 | + | 1068 | WP_000080105.1 | bifunctional histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase HisB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | S1P977 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9LNR0 |