Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 4903150..4903371 Replicon chromosome
Accession NZ_CP124424
Organism Escherichia coli strain AVS0247

Toxin (Protein)


Gene name ldrD Uniprot ID A0A1U9U3P9
Locus tag QJB03_RS23850 Protein ID WP_001531632.1
Coordinates 4903150..4903257 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 4903305..4903371 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJB03_RS23825 (4898994) 4898994..4900076 + 1083 WP_000804726.1 peptide chain release factor 1 -
QJB03_RS23830 (4900076) 4900076..4900909 + 834 WP_000456450.1 peptide chain release factor N(5)-glutamine methyltransferase -
QJB03_RS23835 (4900906) 4900906..4901298 + 393 WP_000200375.1 invasion regulator SirB2 -
QJB03_RS23840 (4901302) 4901302..4902111 + 810 WP_001257044.1 invasion regulator SirB1 -
QJB03_RS23845 (4902147) 4902147..4903001 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
QJB03_RS23850 (4903150) 4903150..4903257 - 108 WP_001531632.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (4903307) 4903307..4903370 + 64 NuclAT_12 - -
- (4903307) 4903307..4903370 + 64 NuclAT_12 - -
- (4903307) 4903307..4903370 + 64 NuclAT_12 - -
- (4903307) 4903307..4903370 + 64 NuclAT_12 - -
- (4903307) 4903307..4903370 + 64 NuclAT_13 - -
- (4903307) 4903307..4903370 + 64 NuclAT_13 - -
- (4903307) 4903307..4903370 + 64 NuclAT_13 - -
- (4903307) 4903307..4903370 + 64 NuclAT_13 - -
- (4903307) 4903307..4903370 + 64 NuclAT_14 - -
- (4903307) 4903307..4903370 + 64 NuclAT_14 - -
- (4903307) 4903307..4903370 + 64 NuclAT_14 - -
- (4903307) 4903307..4903370 + 64 NuclAT_14 - -
- (4903307) 4903307..4903370 + 64 NuclAT_15 - -
- (4903307) 4903307..4903370 + 64 NuclAT_15 - -
- (4903307) 4903307..4903370 + 64 NuclAT_15 - -
- (4903307) 4903307..4903370 + 64 NuclAT_15 - -
- (4903307) 4903307..4903370 + 64 NuclAT_16 - -
- (4903307) 4903307..4903370 + 64 NuclAT_16 - -
- (4903307) 4903307..4903370 + 64 NuclAT_16 - -
- (4903307) 4903307..4903370 + 64 NuclAT_16 - -
- (4903307) 4903307..4903370 + 64 NuclAT_17 - -
- (4903307) 4903307..4903370 + 64 NuclAT_17 - -
- (4903307) 4903307..4903370 + 64 NuclAT_17 - -
- (4903307) 4903307..4903370 + 64 NuclAT_17 - -
- (4903305) 4903305..4903371 + 67 NuclAT_10 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_10 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_10 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_10 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_5 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_5 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_5 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_5 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_6 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_6 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_6 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_6 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_7 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_7 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_7 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_7 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_8 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_8 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_8 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_8 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_9 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_9 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_9 - Antitoxin
- (4903305) 4903305..4903371 + 67 NuclAT_9 - Antitoxin
- (4903307) 4903307..4903372 + 66 NuclAT_18 - -
- (4903307) 4903307..4903372 + 66 NuclAT_18 - -
- (4903307) 4903307..4903372 + 66 NuclAT_18 - -
- (4903307) 4903307..4903372 + 66 NuclAT_18 - -
- (4903307) 4903307..4903372 + 66 NuclAT_19 - -
- (4903307) 4903307..4903372 + 66 NuclAT_19 - -
- (4903307) 4903307..4903372 + 66 NuclAT_19 - -
- (4903307) 4903307..4903372 + 66 NuclAT_19 - -
- (4903307) 4903307..4903372 + 66 NuclAT_20 - -
- (4903307) 4903307..4903372 + 66 NuclAT_20 - -
- (4903307) 4903307..4903372 + 66 NuclAT_20 - -
- (4903307) 4903307..4903372 + 66 NuclAT_20 - -
- (4903307) 4903307..4903372 + 66 NuclAT_21 - -
- (4903307) 4903307..4903372 + 66 NuclAT_21 - -
- (4903307) 4903307..4903372 + 66 NuclAT_21 - -
- (4903307) 4903307..4903372 + 66 NuclAT_21 - -
- (4903307) 4903307..4903372 + 66 NuclAT_22 - -
- (4903307) 4903307..4903372 + 66 NuclAT_22 - -
- (4903307) 4903307..4903372 + 66 NuclAT_22 - -
- (4903307) 4903307..4903372 + 66 NuclAT_22 - -
- (4903307) 4903307..4903372 + 66 NuclAT_23 - -
- (4903307) 4903307..4903372 + 66 NuclAT_23 - -
- (4903307) 4903307..4903372 + 66 NuclAT_23 - -
- (4903307) 4903307..4903372 + 66 NuclAT_23 - -
QJB03_RS23855 (4903662) 4903662..4904762 - 1101 WP_000063608.1 sodium-potassium/proton antiporter ChaA -
QJB03_RS23860 (4905032) 4905032..4905271 + 240 WP_000120702.1 putative cation transport regulator ChaB -
QJB03_RS23865 (4905420) 4905420..4906115 + 696 WP_001295621.1 glutathione-specific gamma-glutamylcyclotransferase -
QJB03_RS23870 (4906159) 4906159..4906512 - 354 WP_001169659.1 DsrE/F sulfur relay family protein YchN -
QJB03_RS23875 (4906697) 4906697..4908091 + 1395 WP_000086187.1 inverse autotransporter invasin YchO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4040.89 Da        Isoelectric Point: 12.5163

>T280199 WP_001531632.1 NZ_CP124424:c4903257-4903150 [Escherichia coli]
MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT280199 NZ_CP124424:4903305-4903371 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1U9U3P9

Antitoxin

Download structure file

References