Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 4840261..4840482 Replicon chromosome
Accession NZ_CP124405
Organism Escherichia coli strain AVS0935

Toxin (Protein)


Gene name ldrD Uniprot ID A0A1U9U3P9
Locus tag QJB05_RS23425 Protein ID WP_001531632.1
Coordinates 4840261..4840368 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 4840416..4840482 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJB05_RS23400 (4836105) 4836105..4837187 + 1083 WP_000804726.1 peptide chain release factor 1 -
QJB05_RS23405 (4837187) 4837187..4838020 + 834 WP_000456450.1 peptide chain release factor N(5)-glutamine methyltransferase -
QJB05_RS23410 (4838017) 4838017..4838409 + 393 WP_000200375.1 invasion regulator SirB2 -
QJB05_RS23415 (4838413) 4838413..4839222 + 810 WP_001257044.1 invasion regulator SirB1 -
QJB05_RS23420 (4839258) 4839258..4840112 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
QJB05_RS23425 (4840261) 4840261..4840368 - 108 WP_001531632.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (4840418) 4840418..4840481 + 64 NuclAT_12 - -
- (4840418) 4840418..4840481 + 64 NuclAT_12 - -
- (4840418) 4840418..4840481 + 64 NuclAT_12 - -
- (4840418) 4840418..4840481 + 64 NuclAT_12 - -
- (4840418) 4840418..4840481 + 64 NuclAT_13 - -
- (4840418) 4840418..4840481 + 64 NuclAT_13 - -
- (4840418) 4840418..4840481 + 64 NuclAT_13 - -
- (4840418) 4840418..4840481 + 64 NuclAT_13 - -
- (4840418) 4840418..4840481 + 64 NuclAT_14 - -
- (4840418) 4840418..4840481 + 64 NuclAT_14 - -
- (4840418) 4840418..4840481 + 64 NuclAT_14 - -
- (4840418) 4840418..4840481 + 64 NuclAT_14 - -
- (4840418) 4840418..4840481 + 64 NuclAT_15 - -
- (4840418) 4840418..4840481 + 64 NuclAT_15 - -
- (4840418) 4840418..4840481 + 64 NuclAT_15 - -
- (4840418) 4840418..4840481 + 64 NuclAT_15 - -
- (4840418) 4840418..4840481 + 64 NuclAT_16 - -
- (4840418) 4840418..4840481 + 64 NuclAT_16 - -
- (4840418) 4840418..4840481 + 64 NuclAT_16 - -
- (4840418) 4840418..4840481 + 64 NuclAT_16 - -
- (4840418) 4840418..4840481 + 64 NuclAT_17 - -
- (4840418) 4840418..4840481 + 64 NuclAT_17 - -
- (4840418) 4840418..4840481 + 64 NuclAT_17 - -
- (4840418) 4840418..4840481 + 64 NuclAT_17 - -
- (4840416) 4840416..4840482 + 67 NuclAT_10 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_10 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_10 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_10 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_5 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_5 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_5 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_5 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_6 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_6 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_6 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_6 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_7 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_7 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_7 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_7 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_8 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_8 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_8 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_8 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_9 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_9 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_9 - Antitoxin
- (4840416) 4840416..4840482 + 67 NuclAT_9 - Antitoxin
- (4840418) 4840418..4840483 + 66 NuclAT_18 - -
- (4840418) 4840418..4840483 + 66 NuclAT_18 - -
- (4840418) 4840418..4840483 + 66 NuclAT_18 - -
- (4840418) 4840418..4840483 + 66 NuclAT_18 - -
- (4840418) 4840418..4840483 + 66 NuclAT_19 - -
- (4840418) 4840418..4840483 + 66 NuclAT_19 - -
- (4840418) 4840418..4840483 + 66 NuclAT_19 - -
- (4840418) 4840418..4840483 + 66 NuclAT_19 - -
- (4840418) 4840418..4840483 + 66 NuclAT_20 - -
- (4840418) 4840418..4840483 + 66 NuclAT_20 - -
- (4840418) 4840418..4840483 + 66 NuclAT_20 - -
- (4840418) 4840418..4840483 + 66 NuclAT_20 - -
- (4840418) 4840418..4840483 + 66 NuclAT_21 - -
- (4840418) 4840418..4840483 + 66 NuclAT_21 - -
- (4840418) 4840418..4840483 + 66 NuclAT_21 - -
- (4840418) 4840418..4840483 + 66 NuclAT_21 - -
- (4840418) 4840418..4840483 + 66 NuclAT_22 - -
- (4840418) 4840418..4840483 + 66 NuclAT_22 - -
- (4840418) 4840418..4840483 + 66 NuclAT_22 - -
- (4840418) 4840418..4840483 + 66 NuclAT_22 - -
- (4840418) 4840418..4840483 + 66 NuclAT_23 - -
- (4840418) 4840418..4840483 + 66 NuclAT_23 - -
- (4840418) 4840418..4840483 + 66 NuclAT_23 - -
- (4840418) 4840418..4840483 + 66 NuclAT_23 - -
QJB05_RS23430 (4840773) 4840773..4841873 - 1101 WP_000063608.1 sodium-potassium/proton antiporter ChaA -
QJB05_RS23435 (4842143) 4842143..4842382 + 240 WP_000120702.1 putative cation transport regulator ChaB -
QJB05_RS23440 (4842531) 4842531..4843226 + 696 WP_001295621.1 glutathione-specific gamma-glutamylcyclotransferase -
QJB05_RS23445 (4843270) 4843270..4843623 - 354 WP_001169659.1 DsrE/F sulfur relay family protein YchN -
QJB05_RS23450 (4843808) 4843808..4845202 + 1395 WP_000086187.1 inverse autotransporter invasin YchO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4040.89 Da        Isoelectric Point: 12.5163

>T280064 WP_001531632.1 NZ_CP124405:c4840368-4840261 [Escherichia coli]
MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT280064 NZ_CP124405:4840416-4840482 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1U9U3P9

Antitoxin

Download structure file

References