Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 4963798..4964019 Replicon chromosome
Accession NZ_CP124387
Organism Escherichia coli strain AVS0972

Toxin (Protein)


Gene name ldrD Uniprot ID A0A1U9U3P9
Locus tag QJB01_RS24105 Protein ID WP_001531632.1
Coordinates 4963798..4963905 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 4963953..4964019 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QJB01_RS24080 (4959642) 4959642..4960724 + 1083 WP_000804726.1 peptide chain release factor 1 -
QJB01_RS24085 (4960724) 4960724..4961557 + 834 WP_000456450.1 peptide chain release factor N(5)-glutamine methyltransferase -
QJB01_RS24090 (4961554) 4961554..4961946 + 393 WP_000200375.1 invasion regulator SirB2 -
QJB01_RS24095 (4961950) 4961950..4962759 + 810 WP_001257044.1 invasion regulator SirB1 -
QJB01_RS24100 (4962795) 4962795..4963649 + 855 WP_000811065.1 3-deoxy-8-phosphooctulonate synthase -
QJB01_RS24105 (4963798) 4963798..4963905 - 108 WP_001531632.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- (4963955) 4963955..4964018 + 64 NuclAT_12 - -
- (4963955) 4963955..4964018 + 64 NuclAT_12 - -
- (4963955) 4963955..4964018 + 64 NuclAT_12 - -
- (4963955) 4963955..4964018 + 64 NuclAT_12 - -
- (4963955) 4963955..4964018 + 64 NuclAT_13 - -
- (4963955) 4963955..4964018 + 64 NuclAT_13 - -
- (4963955) 4963955..4964018 + 64 NuclAT_13 - -
- (4963955) 4963955..4964018 + 64 NuclAT_13 - -
- (4963955) 4963955..4964018 + 64 NuclAT_14 - -
- (4963955) 4963955..4964018 + 64 NuclAT_14 - -
- (4963955) 4963955..4964018 + 64 NuclAT_14 - -
- (4963955) 4963955..4964018 + 64 NuclAT_14 - -
- (4963955) 4963955..4964018 + 64 NuclAT_15 - -
- (4963955) 4963955..4964018 + 64 NuclAT_15 - -
- (4963955) 4963955..4964018 + 64 NuclAT_15 - -
- (4963955) 4963955..4964018 + 64 NuclAT_15 - -
- (4963955) 4963955..4964018 + 64 NuclAT_16 - -
- (4963955) 4963955..4964018 + 64 NuclAT_16 - -
- (4963955) 4963955..4964018 + 64 NuclAT_16 - -
- (4963955) 4963955..4964018 + 64 NuclAT_16 - -
- (4963955) 4963955..4964018 + 64 NuclAT_17 - -
- (4963955) 4963955..4964018 + 64 NuclAT_17 - -
- (4963955) 4963955..4964018 + 64 NuclAT_17 - -
- (4963955) 4963955..4964018 + 64 NuclAT_17 - -
- (4963953) 4963953..4964019 + 67 NuclAT_10 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_10 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_10 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_10 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_5 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_5 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_5 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_5 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_6 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_6 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_6 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_6 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_7 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_7 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_7 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_7 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_8 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_8 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_8 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_8 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_9 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_9 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_9 - Antitoxin
- (4963953) 4963953..4964019 + 67 NuclAT_9 - Antitoxin
- (4963955) 4963955..4964020 + 66 NuclAT_18 - -
- (4963955) 4963955..4964020 + 66 NuclAT_18 - -
- (4963955) 4963955..4964020 + 66 NuclAT_18 - -
- (4963955) 4963955..4964020 + 66 NuclAT_18 - -
- (4963955) 4963955..4964020 + 66 NuclAT_19 - -
- (4963955) 4963955..4964020 + 66 NuclAT_19 - -
- (4963955) 4963955..4964020 + 66 NuclAT_19 - -
- (4963955) 4963955..4964020 + 66 NuclAT_19 - -
- (4963955) 4963955..4964020 + 66 NuclAT_20 - -
- (4963955) 4963955..4964020 + 66 NuclAT_20 - -
- (4963955) 4963955..4964020 + 66 NuclAT_20 - -
- (4963955) 4963955..4964020 + 66 NuclAT_20 - -
- (4963955) 4963955..4964020 + 66 NuclAT_21 - -
- (4963955) 4963955..4964020 + 66 NuclAT_21 - -
- (4963955) 4963955..4964020 + 66 NuclAT_21 - -
- (4963955) 4963955..4964020 + 66 NuclAT_21 - -
- (4963955) 4963955..4964020 + 66 NuclAT_22 - -
- (4963955) 4963955..4964020 + 66 NuclAT_22 - -
- (4963955) 4963955..4964020 + 66 NuclAT_22 - -
- (4963955) 4963955..4964020 + 66 NuclAT_22 - -
- (4963955) 4963955..4964020 + 66 NuclAT_23 - -
- (4963955) 4963955..4964020 + 66 NuclAT_23 - -
- (4963955) 4963955..4964020 + 66 NuclAT_23 - -
- (4963955) 4963955..4964020 + 66 NuclAT_23 - -
QJB01_RS24110 (4964310) 4964310..4965410 - 1101 WP_000063608.1 sodium-potassium/proton antiporter ChaA -
QJB01_RS24115 (4965680) 4965680..4965919 + 240 WP_000120702.1 putative cation transport regulator ChaB -
QJB01_RS24120 (4966068) 4966068..4966763 + 696 WP_001295621.1 glutathione-specific gamma-glutamylcyclotransferase -
QJB01_RS24125 (4966807) 4966807..4967160 - 354 WP_001169659.1 DsrE/F sulfur relay family protein YchN -
QJB01_RS24130 (4967345) 4967345..4968739 + 1395 WP_000086187.1 inverse autotransporter invasin YchO -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4040.89 Da        Isoelectric Point: 12.5163

>T280002 WP_001531632.1 NZ_CP124387:c4963905-4963798 [Escherichia coli]
MTLAQFAMIFWHNLAAPILAGIITAVIVSWWRNRK

Download         Length: 108 bp

Antitoxin


Download         Length: 67 bp

>AT280002 NZ_CP124387:4963953-4964019 [Escherichia coli]
GTTCTGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTGTACCTCTCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1U9U3P9

Antitoxin

Download structure file

References