Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 63372..64213 Replicon plasmid pLX02
Accession NZ_CP123976
Organism Thioclava nitratireducens strain M1-LQ-LJL-11

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag P0N61_RS20525 Protein ID WP_088726111.1
Coordinates 63372..63890 (-) Length 173 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag P0N61_RS20530 Protein ID WP_088726120.1
Coordinates 63887..64213 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P0N61_RS20515 (P0N61_20515) 58707..62969 - 4263 WP_088726112.1 strawberry notch family protein -
P0N61_RS20520 (P0N61_20520) 63072..63224 - 153 WP_075777220.1 StaA -
P0N61_RS20525 (P0N61_20525) 63372..63890 - 519 WP_088726111.1 type II toxin-antitoxin system YhaV family toxin Toxin
P0N61_RS20530 (P0N61_20530) 63887..64213 - 327 WP_088726120.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
P0N61_RS20535 (P0N61_20535) 64338..64991 - 654 WP_075777222.1 hypothetical protein -
P0N61_RS20540 (P0N61_20540) 65094..65687 - 594 WP_088726110.1 regulator -
P0N61_RS20545 (P0N61_20545) 65762..67744 - 1983 WP_088726109.1 ParB/RepB/Spo0J family partition protein -
P0N61_RS20550 (P0N61_20550) 67901..68290 - 390 WP_088726108.1 DUF3768 domain-containing protein -
P0N61_RS20555 (P0N61_20555) 68378..68587 - 210 WP_088726107.1 DUF6330 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..131650 131650


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(19-155)

Antitoxin

PrlF antitoxin

(9-104)


Sequences

Toxin        


Download         Length: 173 a.a.        Molecular weight: 19249.90 Da        Isoelectric Point: 9.8076

>T279294 WP_088726111.1 NZ_CP123976:c63890-63372 [Thioclava nitratireducens]
MSGDSVPAGAPLVVNGWTIYAHPLFLDQLEGLILELEARKARDPKTWRKKNSAKRLAAIFKLVTEAIPADPGAAAFRQGG
TLGDHRKHWFRAKFFQQYRLFYRFNSDAKVIVVAWVNDDKTLRAYGSKTDAYATFKGMLEDGNPPENFDALLKEAAAADK
RFETSLEAATDR

Download         Length: 519 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11868.33 Da        Isoelectric Point: 4.3722

>AT279294 WP_088726120.1 NZ_CP123976:c64213-63887 [Thioclava nitratireducens]
MTVLTQDVSKLTDRYQTTVPAGVRKQLKLGKGDQIRYCTEPSGRVYIEPVRSDEDDPALGAFLDFVEADIKAHPDRIRAF
DGALHGRLAALVGDVDVDLDAPLSLEDE

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References