Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type I Classification (family/domain) hok-sok/-
Location 504034..504259 Replicon chromosome
Accession NZ_CP123966
Organism Lysinibacillus sp.

Toxin (Protein)


Gene name hokW Uniprot ID -
Locus tag QH639_RS02700 Protein ID WP_281115638.1
Coordinates 504104..504259 (+) Length 52 a.a.

Antitoxin (RNA)


Gene name sokW
Locus tag -
Coordinates 504034..504092 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QH639_RS02675 (499579) 499579..500178 + 600 WP_281115636.1 Ail/Lom family outer membrane beta-barrel protein -
QH639_RS02680 (500243) 500243..500548 + 306 WP_281115637.1 DUF977 family protein -
QH639_RS02685 (500872) 500872..501111 + 240 WP_001367360.1 hypothetical protein -
QH639_RS02690 (501114) 501114..501710 + 597 WP_032286199.1 hypothetical protein -
QH639_RS02695 (501934) 501934..503658 + 1725 WP_000479014.1 DUF2326 domain-containing protein -
- (504034) 504034..504092 - 59 NuclAT_0 - Antitoxin
- (504034) 504034..504092 - 59 NuclAT_0 - Antitoxin
QH639_RS02700 (504104) 504104..504259 + 156 WP_281115638.1 Hok/Gef family protein Toxin
QH639_RS02705 (504780) 504780..506081 - 1302 WP_131522313.1 NCS2 family permease -
QH639_RS02710 (506524) 506524..507192 - 669 WP_237898753.1 MOSC domain-containing protein -
QH639_RS02715 (507367) 507367..508920 - 1554 WP_131522315.1 glutamine-hydrolyzing GMP synthase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-40)


Sequences


Toxin        


Download         Length: 52 a.a.        Molecular weight: 5731.00 Da        Isoelectric Point: 10.1323

>T279289 WP_281115638.1 NZ_CP123966:504104-504259 [Lysinibacillus sp. 1 U-2021]
MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEGLPTCYSPVRR

Download         Length: 156 bp


Antitoxin


Download         Length: 59 bp

>AT279289 NZ_CP123966:c504092-504034 [Lysinibacillus sp. 1 U-2021]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGTCTAGCATGAAATTGGCCTCA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Download structure file

References