Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3723713..3724413 Replicon chromosome
Accession NZ_CP123897
Organism Methylomonas sp. UP202

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag QC632_RS16565 Protein ID WP_281020839.1
Coordinates 3724117..3724413 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag QC632_RS16560 Protein ID WP_281020838.1
Coordinates 3723713..3724114 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC632_RS16540 (QC632_16540) 3719573..3719941 + 369 WP_281020834.1 XRE family transcriptional regulator -
QC632_RS16545 (QC632_16545) 3720045..3720572 + 528 WP_281020835.1 SLATT domain-containing protein -
QC632_RS16550 (QC632_16550) 3720569..3722383 + 1815 WP_281020836.1 RelA/SpoT domain-containing protein -
QC632_RS16555 (QC632_16555) 3723087..3723584 + 498 WP_281020837.1 hypothetical protein -
QC632_RS16560 (QC632_16560) 3723713..3724114 - 402 WP_281020838.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
QC632_RS16565 (QC632_16565) 3724117..3724413 - 297 WP_281020839.1 type II toxin-antitoxin system MqsR family toxin Toxin
QC632_RS16575 (QC632_16575) 3724813..3725655 - 843 WP_064028563.1 sulfite exporter TauE/SafE family protein -
QC632_RS16580 (QC632_16580) 3725656..3728106 - 2451 WP_281020840.1 heavy metal translocating P-type ATPase -
QC632_RS16585 (QC632_16585) 3728176..3728790 - 615 WP_168033448.1 hypothetical protein -
QC632_RS16590 (QC632_16590) 3728884..3729072 - 189 WP_281020841.1 hypothetical protein -
QC632_RS16595 (QC632_16595) 3729194..3729388 - 195 WP_281020842.1 heavy metal translocating P-type ATPase metal-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(5-97)

Antitoxin

Zinc finger, MqsA-type

(3-48)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 10872.61 Da        Isoelectric Point: 6.7163

>T279201 WP_281020839.1 NZ_CP123897:c3724413-3724117 [Methylomonas sp. UP202]
MEKQTPHCKLSVIKALIADGKIRTTKSAREGAAALGFDFDDMLAVILELTGADFYKSMSTHADHKVWQDVYRPKTVAGDV
YLKLTVVDDVLVVSFKEL

Download         Length: 297 bp

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14670.83 Da        Isoelectric Point: 4.6599

>AT279201 WP_281020838.1 NZ_CP123897:c3724114-3723713 [Methylomonas sp. UP202]
MKCPSCGAAELVGDTRDMPYIYKGESTMIPDVTGEFCPACDEVITDADESRRTMALMIEFNKQVNASIVDPSFIASVRKK
LALDQKEASEIFGGGINAFSRYENGKTKPPLALVKLLKVLDRHPDLLDEVRTD

Download         Length: 402 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References