Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2335880..2336064 Replicon chromosome
Accession NZ_CP123853
Organism Staphylococcus aureus strain FDA209P

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NUG19_RS11415 Protein ID WP_000482647.1
Coordinates 2335880..2335987 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2336004..2336064 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUG19_RS11390 2331252..2331725 + 474 WP_000456489.1 GyrI-like domain-containing protein -
NUG19_RS11395 2331848..2333059 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
NUG19_RS11400 2333241..2333900 - 660 WP_000831298.1 membrane protein -
NUG19_RS11405 2333960..2335102 - 1143 WP_042727740.1 glycerate kinase -
NUG19_RS11410 2335360..2335746 + 387 WP_000779360.1 flippase GtxA -
NUG19_RS11415 2335880..2335987 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2336004..2336064 - 61 - - Antitoxin
NUG19_RS11420 2336691..2338454 + 1764 WP_001064814.1 ABC transporter ATP-binding protein -
NUG19_RS11425 2338479..2340212 + 1734 WP_000486494.1 ABC transporter ATP-binding protein -
NUG19_RS11430 2340443..2340610 + 168 WP_001790576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T279186 WP_000482647.1 NZ_CP123853:2335880-2335987 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT279186 NZ_CP123853:c2336064-2336004 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACTAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References