Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2335879..2336063 Replicon chromosome
Accession NZ_CP123852
Organism Staphylococcus aureus strain 5812R

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag NRK31_RS11415 Protein ID WP_000482647.1
Coordinates 2335879..2335986 (+) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2336003..2336063 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NRK31_RS11390 2331251..2331724 + 474 WP_000456489.1 GyrI-like domain-containing protein -
NRK31_RS11395 2331847..2333058 - 1212 WP_001192075.1 multidrug effflux MFS transporter -
NRK31_RS11400 2333240..2333899 - 660 WP_000831298.1 membrane protein -
NRK31_RS11405 2333959..2335101 - 1143 WP_042727740.1 glycerate kinase -
NRK31_RS11410 2335359..2335745 + 387 WP_000779360.1 flippase GtxA -
NRK31_RS11415 2335879..2335986 + 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
- 2336003..2336063 - 61 - - Antitoxin
NRK31_RS11420 2336690..2338453 + 1764 WP_001064814.1 ABC transporter ATP-binding protein -
NRK31_RS11425 2338478..2340211 + 1734 WP_000486494.1 ABC transporter ATP-binding protein -
NRK31_RS11430 2340442..2340609 + 168 WP_001790576.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T279175 WP_000482647.1 NZ_CP123852:2335879-2335986 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT279175 NZ_CP123852:c2336063-2336003 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACTAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References