Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2025290..2025877 Replicon chromosome
Accession NZ_CP123843
Organism Agrobacterium fabrum strain N40/94

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag G6L42_RS09970 Protein ID WP_080807502.1
Coordinates 2025290..2025574 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag G6L42_RS09975 Protein ID WP_080807499.1
Coordinates 2025626..2025877 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G6L42_RS09945 (G6L42_009945) 2020769..2021383 - 615 WP_244520223.1 hypothetical protein -
G6L42_RS09950 (G6L42_009950) 2021570..2022703 + 1134 WP_167305544.1 alpha-hydroxy acid oxidase -
G6L42_RS09955 (G6L42_009955) 2022900..2023244 - 345 WP_006311727.1 multidrug efflux SMR transporter -
G6L42_RS09960 (G6L42_009960) 2023241..2023825 - 585 WP_010972227.1 TetR/AcrR family transcriptional regulator -
G6L42_RS09965 (G6L42_009965) 2024015..2025286 + 1272 WP_167305628.1 D-alanyl-D-alanine carboxypeptidase -
G6L42_RS09970 (G6L42_009970) 2025290..2025574 - 285 WP_080807502.1 Txe/YoeB family addiction module toxin Toxin
G6L42_RS09975 (G6L42_009975) 2025626..2025877 - 252 WP_080807499.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
G6L42_RS09980 (G6L42_009980) 2025930..2026679 - 750 WP_080807496.1 metallophosphoesterase family protein -
G6L42_RS09985 (G6L42_009985) 2026685..2027041 - 357 WP_006311723.1 hydroxyisourate hydrolase -
G6L42_RS09990 (G6L42_009990) 2027038..2027538 - 501 WP_080807493.1 ureidoglycolate lyase -
G6L42_RS09995 (G6L42_009995) 2027542..2027904 - 363 WP_010972232.1 DUF86 domain-containing protein -
G6L42_RS10000 (G6L42_010000) 2027901..2028194 - 294 WP_010972233.1 nucleotidyltransferase family protein -
G6L42_RS10005 (G6L42_010005) 2028248..2028745 - 498 WP_080807490.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
G6L42_RS10010 (G6L42_010010) 2028745..2029668 - 924 WP_080807485.1 allantoinase PuuE -
G6L42_RS10015 (G6L42_010015) 2029870..2030577 - 708 WP_080807479.1 DUF1045 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(10-94)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11487.22 Da        Isoelectric Point: 9.5189

>T279160 WP_080807502.1 NZ_CP123843:c2025574-2025290 [Agrobacterium fabrum]
MQQKGTIALGWSHEGWEDYLHWQKYDRKMLERINELIKDCRRHPFEGIGKPEPLRFQLKGLWSRRISQEHRLVYELRGDG
EKAVLIIHQCRFHY

Download         Length: 285 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9394.61 Da        Isoelectric Point: 4.5242

>AT279160 WP_080807499.1 NZ_CP123843:c2025877-2025626 [Agrobacterium fabrum]
MRTVIFSKARESLASLLDEVSQDRVAVEIVRRDKPSAVLIDKDEYEGLLETLHLCSSPENFARLRKSMSDVDTGVFESHD
LID

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References