Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-HTH
Location 807..1392 Replicon plasmid pAP8900-3
Accession NZ_CP123768
Organism Acinetobacter pittii strain AP8900

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QFB56_RS20145 Protein ID WP_199953194.1
Coordinates 1072..1392 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QFB56_RS20140 Protein ID WP_000369783.1
Coordinates 807..1079 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QFB56_RS20140 (QFB56_20140) 807..1079 - 273 WP_000369783.1 NadS family protein Antitoxin
QFB56_RS20145 (QFB56_20145) 1072..1392 - 321 WP_199953194.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QFB56_RS20150 (QFB56_20150) 1625..2539 + 915 WP_199953193.1 Abi family protein -
QFB56_RS20155 (QFB56_20155) 2558..3199 + 642 WP_199953192.1 tetratricopeptide repeat protein -
QFB56_RS20160 (QFB56_20160) 3227..4873 - 1647 WP_001094416.1 IS66-like element ISAba17 family transposase -
QFB56_RS20165 (QFB56_20165) 4948..5283 - 336 WP_000618090.1 IS66 family insertion sequence element accessory protein TnpB -
QFB56_RS20170 (QFB56_20170) 5280..5708 - 429 WP_000364662.1 transposase -
QFB56_RS20175 (QFB56_20175) 5847..6236 + 390 WP_199953189.1 SEL1-like repeat protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..12558 12558


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(38-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(37-85)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12223.09 Da        Isoelectric Point: 6.9809

>T279142 WP_199953194.1 NZ_CP123768:c1392-1072 [Acinetobacter pittii]
MLFIETSIFTKQIKELVSDDEYRELQQELLVQPDKGDLIKNGGGIRKVRCAQGSKGKSGGIRVIYYWITEDDQIFMLLAY
PKSVKENLTDKETTILRQLVKEQFHG

Download         Length: 321 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10094.49 Da        Isoelectric Point: 7.2040

>AT279142 WP_000369783.1 NZ_CP123768:c1079-807 [Acinetobacter pittii]
MDNNLFDDLVASIKEAGAIKRNEVQASRVTELTLPDIKEVREKTGLSQTEFAARLHISPRTLQNWEQGRRYPTGPAATLI
RILDAHPSLI

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References