Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1163347..1163852 Replicon chromosome
Accession NZ_CP123499
Organism Arsenophonus sp. aPb

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag QE177_RS05140 Protein ID WP_280551704.1
Coordinates 1163347..1163604 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag QE177_RS05145 Protein ID WP_280551706.1
Coordinates 1163601..1163852 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QE177_RS05125 (QE177_05125) 1159784..1160401 + 618 WP_280551700.1 outer membrane lipoprotein chaperone LolA -
QE177_RS05130 (QE177_05130) 1160403..1161746 + 1344 WP_280552217.1 replication-associated recombination protein A -
QE177_RS05135 (QE177_05135) 1161856..1163148 + 1293 WP_280551702.1 serine--tRNA ligase -
QE177_RS05140 (QE177_05140) 1163347..1163604 - 258 WP_280551704.1 Txe/YoeB family addiction module toxin Toxin
QE177_RS05145 (QE177_05145) 1163601..1163852 - 252 WP_280551706.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
QE177_RS05150 (QE177_05150) 1164408..1164665 - 258 WP_280551709.1 bacteriocin immunity protein -
QE177_RS05155 (QE177_05155) 1164667..1165215 - 549 WP_280551711.1 HNH endonuclease signature motif containing protein -
QE177_RS05160 (QE177_05160) 1165199..1165411 + 213 WP_280551713.1 hypothetical protein -
QE177_RS05165 (QE177_05165) 1165590..1165850 - 261 WP_280551715.1 bacteriocin immunity protein -
QE177_RS05170 (QE177_05170) 1165852..1166247 - 396 WP_280551716.1 HNH endonuclease signature motif containing protein -
QE177_RS05175 (QE177_05175) 1166316..1166588 - 273 WP_180560955.1 colicin immunity domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10465.13 Da        Isoelectric Point: 9.8432

>T279007 WP_280551704.1 NZ_CP123499:c1163604-1163347 [Arsenophonus sp. aPb]
MKLIFTEQSWNDYLYWQQIDKKIIKRINELIKDIKREPFSGIGKPEPLKHNLTAFWSRRITEEHRLIYRLTDKGLEIASC
RYYYN

Download         Length: 258 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9415.67 Da        Isoelectric Point: 4.4217

>AT279007 WP_280551706.1 NZ_CP123499:c1163852-1163601 [Arsenophonus sp. aPb]
MKTVNYTDARQNLTSIMNEAIDDRIPILITRQKGIPCVLLSLDEYQSLEETAYLLRSPANARHLLDSIDELNAGKGIERD
IQE

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References