Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 1301671..1302298 Replicon chromosome
Accession NZ_CP123498
Organism Arsenophonus nasoniae strain aIh

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QE207_RS08300 Protein ID WP_280630001.1
Coordinates 1301969..1302298 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag QE207_RS08295 Protein ID WP_280630000.1
Coordinates 1301671..1301979 (-) Length 103 a.a.

Genomic Context

QE207_RS08260QE207_RS08280QE207_RS08285QE207_RS08290QE207_RS08305QE207_RS08310QE207_RS08315QE207_RS08320QE207_RS08325QE207_RS08330QE207_RS08250QE207_RS08255QE207_RS08265QE207_RS08270QE207_RS08275QE207_RS08295QE207_RS08300
Location: 1298708..1298890 (183 bp)
Type: Others
Protein ID: WP_280629810.1
Location: 1300452..1300679 (228 bp)
Type: Others
Protein ID: WP_280629998.1
Location: 1300712..1301170 (459 bp)
Type: Others
Protein ID: Protein_1218
Location: 1301238..1301576 (339 bp)
Type: Others
Protein ID: WP_280629999.1
Location: 1302424..1303524 (1101 bp)
Type: Others
Protein ID: WP_280630002.1
Location: 1303515..1303715 (201 bp)
Type: Others
Protein ID: WP_280630003.1
Location: 1303724..1304371 (648 bp)
Type: Others
Protein ID: WP_280630258.1
Location: 1304454..1304693 (240 bp)
Type: Others
Protein ID: WP_280630004.1
Location: 1304697..1304948 (252 bp)
Type: Others
Protein ID: WP_280630259.1
Location: 1304990..1305649 (660 bp)
Type: Others
Protein ID: WP_280630005.1
Location: 1297076..1297435 (360 bp)
Type: Others
Protein ID: WP_280629808.1
Location: 1297976..1298413 (438 bp)
Type: Others
Protein ID: WP_280629995.1
Location: 1298868..1299029 (162 bp)
Type: Others
Protein ID: WP_280629811.1
Location: 1299228..1299506 (279 bp)
Type: Others
Protein ID: WP_280629996.1
Location: 1299713..1300366 (654 bp)
Type: Others
Protein ID: WP_280629997.1
Location: 1301671..1301979 (309 bp)
Type: Antitoxin
Protein ID: WP_280630000.1
Location: 1301969..1302298 (330 bp)
Type: Toxin
Protein ID: WP_280630001.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QE207_RS08250 (QE207_08245)1297076..1297435-360WP_280629808.1hypothetical protein-
QE207_RS08255 (QE207_08250)1297976..1298413-438WP_280629995.1hypothetical protein-
QE207_RS08260 (QE207_08255)1298708..1298890+183WP_280629810.1hypothetical protein-
QE207_RS08265 (QE207_08260)1298868..1299029-162WP_280629811.1hypothetical protein-
QE207_RS08270 (QE207_08265)1299228..1299506-279WP_280629996.1hypothetical protein-
QE207_RS08275 (QE207_08270)1299713..1300366-654WP_280629997.1S24 family peptidase-
QE207_RS08280 (QE207_08275)1300452..1300679+228WP_280629998.1Cro/CI family transcriptional regulator-
QE207_RS08285 (QE207_08280)1300712..1301170+459Protein_1218YmfL family putative regulatory protein-
QE207_RS08290 (QE207_08285)1301238..1301576+339WP_280629999.1DUF4222 domain-containing protein-
QE207_RS08295 (QE207_08290)1301671..1301979-309WP_280630000.1helix-turn-helix transcriptional regulatorAntitoxin
QE207_RS08300 (QE207_08295)1301969..1302298-330WP_280630001.1type II toxin-antitoxin system RelE/ParE family toxinToxin
QE207_RS08305 (QE207_08300)1302424..1303524+1101WP_280630002.1conserved phage C-terminal domain-containing protein-
QE207_RS08310 (QE207_08305)1303515..1303715+201WP_280630003.1hypothetical protein-
QE207_RS08315 (QE207_08310)1303724..1304371+648WP_280630258.1phage N-6-adenine-methyltransferase-
QE207_RS08320 (QE207_08315)1304454..1304693+240WP_280630004.1hypothetical protein-
QE207_RS08325 (QE207_08320)1304697..1304948+252WP_280630259.1DUF968 domain-containing protein-
QE207_RS08330 (QE207_08325)1304990..1305649+660WP_280630005.1bacteriophage antitermination protein Q-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--1246056..133980993753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(15-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-94)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 12669.79 Da        Isoelectric Point: 9.9623

>T279001 WP_280630001.1 NZ_CP123498:c1302298-1301969 [Arsenophonus nasoniae]
MKYTIEYYSEEVRTEIEQLPTSMRVRYTHLVERMKVYGGNLGEPHTSPFGDGLFELRIKSSNGIGRVFYCTLIGKCIVIL
HSFVKKTQKTPVGDLKKAKTRMKEVKHDW

Download         Length: 330 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11274.25 Da        Isoelectric Point: 10.4856

>AT279001 WP_280630000.1 NZ_CP123498:c1301979-1301671 [Arsenophonus nasoniae]
MTGKRISPKMTHDEMVAKWMKDPAFKAEYDAIEEEFALLDEILLARKKAGLTQAQLAERMGTKATAITRMESNLASGVSG
PSFSTLKKLAKATGKKLQIRFV

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References