Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 16905..17437 Replicon plasmid p15628A_320
Accession NZ_CP123373
Organism Providencia rettgeri strain PreM15628

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag KOF27_RS20015 Protein ID WP_140172931.1
Coordinates 16905..17180 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag KOF27_RS20020 Protein ID WP_283656904.1
Coordinates 17174..17437 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KOF27_RS19995 (KOF27_20295) 12839..13117 - 279 WP_180359560.1 hypothetical protein -
KOF27_RS20000 (KOF27_20300) 13353..13868 - 516 WP_125894902.1 hypothetical protein -
KOF27_RS20010 (KOF27_20310) 16694..16804 + 111 WP_257468673.1 arylsulfatase -
KOF27_RS20015 (KOF27_20315) 16905..17180 - 276 WP_140172931.1 type II toxin-antitoxin system YafQ family toxin Toxin
KOF27_RS20020 (KOF27_20320) 17174..17437 - 264 WP_283656904.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KOF27_RS20025 (KOF27_20325) 17610..18239 - 630 WP_180359559.1 recombinase family protein -
KOF27_RS20030 (KOF27_20330) 18416..21442 + 3027 WP_042849110.1 Tn3 family transposase -
KOF27_RS20035 (KOF27_20335) 21525..21698 + 174 WP_180359558.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid mph(E) / msr(E) / blaPER-2 / aph(3')-VI / blaNDM-1 / qnrD1 / aph(3')-Ia / sul1 / qacE / ARR-3 / catB3 / blaOXA-1 / aac(6')-Ib-cr / sul2 / aph(3'')-Ib / aph(6)-Id / tet(A) / floR groEL 1..319669 319669


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-83)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10608.25 Da        Isoelectric Point: 9.9690

>T278967 WP_140172931.1 NZ_CP123373:c17180-16905 [Providencia rettgeri]
MLTPIRSSAFKADVKRQKKRGKDLNKLKVLIELLIKEEQIPADYVDHPLTGNWRGYRDAHIEGDWLLIYKITGQELKLAR
TGSHQDIFSQY

Download         Length: 276 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9357.84 Da        Isoelectric Point: 5.0939

>AT278967 WP_283656904.1 NZ_CP123373:c17437-17174 [Providencia rettgeri]
MISDTTVKARISQDVKERAVSALAKMGLNTSDLIRMVMIRVADEGKLPFDIKTPNVVTKEAIEELEKGNGKAFSSTNALF
DDLGIC

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References