Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 96713..97245 Replicon plasmid p15793A_225
Accession NZ_CP123366
Organism Providencia rettgeri strain PreM15793

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag KOL65_RS20405 Protein ID WP_140172931.1
Coordinates 96713..96988 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag KOL65_RS20410 Protein ID WP_283656904.1
Coordinates 96982..97245 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KOL65_RS20380 (KOL65_20665) 92647..92925 - 279 WP_180359560.1 hypothetical protein -
KOL65_RS20385 (KOL65_20670) 92910..93077 - 168 WP_282553685.1 hypothetical protein -
KOL65_RS20390 (KOL65_20675) 93161..93676 - 516 WP_125894902.1 hypothetical protein -
KOL65_RS20400 (KOL65_20685) 96502..96612 + 111 WP_257468673.1 arylsulfatase -
KOL65_RS20405 (KOL65_20690) 96713..96988 - 276 WP_140172931.1 type II toxin-antitoxin system YafQ family toxin Toxin
KOL65_RS20410 (KOL65_20695) 96982..97245 - 264 WP_283656904.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KOL65_RS20415 (KOL65_20700) 97418..98047 - 630 WP_180359559.1 recombinase family protein -
KOL65_RS20420 (KOL65_20705) 98224..101250 + 3027 WP_042849110.1 Tn3 family transposase -
KOL65_RS20425 (KOL65_20710) 101333..101506 + 174 WP_180359558.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid qnrD1 / aph(3')-Ia / sul1 / qacE / ARR-3 / catB3 / blaOXA-1 / aac(6')-Ib-cr / blaPER-2 / aph(3')-VI / blaNDM-1 groEL 1..224540 224540


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(7-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-83)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10608.25 Da        Isoelectric Point: 9.9690

>T278961 WP_140172931.1 NZ_CP123366:c96988-96713 [Providencia rettgeri]
MLTPIRSSAFKADVKRQKKRGKDLNKLKVLIELLIKEEQIPADYVDHPLTGNWRGYRDAHIEGDWLLIYKITGQELKLAR
TGSHQDIFSQY

Download         Length: 276 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9357.84 Da        Isoelectric Point: 5.0939

>AT278961 WP_283656904.1 NZ_CP123366:c97245-96982 [Providencia rettgeri]
MISDTTVKARISQDVKERAVSALAKMGLNTSDLIRMVMIRVADEGKLPFDIKTPNVVTKEAIEELEKGNGKAFSSTNALF
DDLGIC

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References