Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 3592791..3593329 Replicon chromosome
Accession NZ_CP123280
Organism Salmonella sp. SA17155

Toxin (Protein)


Gene name yafQ Uniprot ID M7RHM1
Locus tag QEN30_RS17840 Protein ID WP_001526148.1
Coordinates 3593054..3593329 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID M7RMV7
Locus tag QEN30_RS17835 Protein ID WP_000729713.1
Coordinates 3592791..3593051 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEN30_RS17815 (3588344) 3588344..3589897 + 1554 WP_000013007.1 TROVE domain-containing protein -
QEN30_RS17820 (3589906) 3589906..3590097 + 192 Protein_3470 TROVE domain-containing protein -
QEN30_RS17825 (3590445) 3590445..3591659 + 1215 WP_001105521.1 RNA-splicing ligase RtcB -
QEN30_RS17830 (3591663) 3591663..3592682 + 1020 WP_000101027.1 RNA 3'-terminal phosphate cyclase -
QEN30_RS17835 (3592791) 3592791..3593051 + 261 WP_000729713.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QEN30_RS17840 (3593054) 3593054..3593329 + 276 WP_001526148.1 type II toxin-antitoxin system YafQ family toxin Toxin
QEN30_RS17845 (3593417) 3593417..3596122 - 2706 WP_000907029.1 HTH-type transcriptional regulator MalT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(4-84)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10739.34 Da        Isoelectric Point: 8.8652

>T278892 WP_001526148.1 NZ_CP123280:3593054-3593329 [Salmonella sp. SA17155]
MGQREIEYSGQFQKDVKRAQKRHKDVGKLKTLMTLLIHHPFPLPAIYKDHPLQGSYSGYRDAHIEPDWILIYKITDECLR
FERTGTHADLF

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9446.80 Da        Isoelectric Point: 4.4734

>AT278892 WP_000729713.1 NZ_CP123280:3592791-3593051 [Salmonella sp. SA17155]
MAANALVRARIDETLKDQAADVLAEMGLTISDLIRITLTKVAREKALPFDLRIPNELTSRTIENSEAGVDIHKAKDADDL
FDQLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3V4SM83

Antitoxin

Source ID Structure
AlphaFold DB A0A4D6P2L2

References