Detailed information of TA system TA278877

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ralR-IsrA/-
• Location: 332379..332748
• Replicon: chromosome
• Accession: NZ_CP123280
• Organism: Salmonella sp. SA17155

Toxin (Protein)

• Gene name: ralR
• Uniprot ID: A0A891STD1
• Locus tag: QEN30_RS01890
• Protein ID: WP_042853000.1
• Coordinates: 332554..332748 (-)
• Length: 65 a.a.

Antitoxin (RNA)

Gene name	IsrA
Locus tag	-
Coordinates	332379..332555 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QEN30_RS01850 (327817)	327817..328473	-	657	WP_000100258.1	carbon-nitrogen hydrolase family protein	-
QEN30_RS01855 (328581)	328581..328811	-	231	WP_000856224.1	DNA polymerase III subunit theta	-
QEN30_RS01860 (328949)	328949..329323	+	375	WP_000168393.1	CopC domain-containing protein YobA	-
QEN30_RS01865 (329324)	329324..330199	+	876	WP_000979702.1	copper homeostasis membrane protein CopD	-
QEN30_RS01870 (330216)	330216..330569	+	354	WP_000722368.1	YebY family protein	-
QEN30_RS01875 (330943)	330943..332019	-	1077	WP_001189085.1	phage integrase Arm DNA-binding domain-containing protein	-
QEN30_RS01880 (331985)	331985..332266	-	282	WP_023234152.1	excisionase	-
- (332379)	332379..332555	+	177	NuclAT_0	-	Antitoxin
- (332379)	332379..332555	+	177	NuclAT_0	-	Antitoxin
- (332379)	332379..332555	+	177	NuclAT_0	-	Antitoxin
- (332379)	332379..332555	+	177	NuclAT_0	-	Antitoxin
QEN30_RS01885 (332373)	332373..332561	-	189	WP_052929118.1	DUF1187 family protein	-
QEN30_RS01890 (332554)	332554..332748	-	195	WP_042853000.1	type I toxin-antitoxin system endodeoxyribonuclease toxin RalR	Toxin
QEN30_RS01895 (332805)	332805..333614	-	810	WP_052929117.1	recombination protein RecT	-
QEN30_RS01900 (333607)	333607..336282	-	2676	WP_052929116.1	exodeoxyribonuclease VIII	-
QEN30_RS01905 (336383)	336383..336658	-	276	WP_080312066.1	hypothetical protein	-
QEN30_RS01910 (336733)	336733..336903	-	171	WP_001359121.1	YdaE family protein	-
QEN30_RS01915 (336903)	336903..337124	-	222	WP_000560226.1	killing protein KilR	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	sopE2	325009..405757	80748

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Endodeoxyribonuclease toxin RalR (6-54)

Sequences

Toxin

Protein

• Length: 65 a.a.
• Molecular weight: 7019.87 Da
• Isoelectric Point: 8.6419

>T278877 WP_042853000.1 NZ_CP123280:c332748-332554 [Salmonella sp. SA17155]
MRYDDVKPCPFCGCPSVTVKAISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV

Nucleotide

• Length: 195 bp

Antitoxin

Nucleotide

• Length: 177 bp

>AT278877 NZ_CP123280:332379-332555 [Salmonella sp. SA17155]
GGACAGAAGTTTCTCGCAATTAAAATTTATCAGCTTTACTTTCTGCTCTCTGGACACGCCTGCTTCTTTTTTCCCTGAGA
GCATTTTTTCGCATTCTGATTTCGTTAATTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCTTTTTCA
ATAGTGGCAGTTATTTT

Structures

Antitoxin