Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 4046732..4046990 Replicon chromosome
Accession NZ_CP123231
Organism Escherichia coli strain 5132

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag QET41_RS19715 Protein ID WP_000809168.1
Coordinates 4046838..4046990 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 4046732..4046789 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QET41_RS19700 4042561..4043820 - 1260 WP_000494929.1 hypothetical protein -
QET41_RS19705 4043949..4045442 - 1494 WP_001774152.1 sulfatase-like hydrolase/transferase -
QET41_RS19710 4045462..4046223 - 762 WP_001274832.1 outer membrane protein OmpK -
- 4046732..4046789 - 58 - - Antitoxin
QET41_RS19715 4046838..4046990 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
QET41_RS19720 4047095..4048225 - 1131 WP_001118464.1 molecular chaperone DnaJ -
QET41_RS19725 4048314..4050230 - 1917 WP_000516135.1 molecular chaperone DnaK -
QET41_RS19730 4050602..4051006 + 405 WP_000843687.1 DUF2541 family protein -
QET41_RS19735 4051032..4051745 + 714 WP_001102391.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T278685 WP_000809168.1 NZ_CP123231:4046838-4046990 [Escherichia coli]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT278685 NZ_CP123231:c4046789-4046732 [Escherichia coli]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References