Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/YoeB-YefM |
Location | 4868011..4868516 | Replicon | chromosome |
Accession | NC_017911 | ||
Organism | Pseudomonas fluorescens A506 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | A0A0W0MVT7 |
Locus tag | PFLA506_RS21815 | Protein ID | WP_014719853.1 |
Coordinates | 4868262..4868516 (+) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | I4K3F7 |
Locus tag | PFLA506_RS21810 | Protein ID | WP_003194039.1 |
Coordinates | 4868011..4868265 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PFLA506_RS21795 | 4863449..4865350 | + | 1902 | WP_014719850.1 | alkaline phosphatase family protein | - |
PFLA506_RS21800 | 4865489..4866502 | + | 1014 | WP_014719851.1 | sensor domain-containing diguanylate cyclase | - |
PFLA506_RS21805 | 4866613..4867866 | + | 1254 | WP_014719852.1 | aspartate aminotransferase family protein | - |
PFLA506_RS21810 | 4868011..4868265 | + | 255 | WP_003194039.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
PFLA506_RS21815 | 4868262..4868516 | + | 255 | WP_014719853.1 | Txe/YoeB family addiction module toxin | Toxin |
PFLA506_RS21820 | 4868615..4869331 | + | 717 | WP_014719854.1 | hypothetical protein | - |
PFLA506_RS21825 | 4869342..4870463 | - | 1122 | WP_014719855.1 | aminotransferase class V-fold PLP-dependent enzyme | - |
PFLA506_RS21830 | 4870465..4871667 | - | 1203 | WP_019817486.1 | MFS transporter | - |
PFLA506_RS21835 | 4871667..4872917 | - | 1251 | WP_014719857.1 | ATP-grasp domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9977.51 Da Isoelectric Point: 8.0456
>T27836 WP_014719853.1 NC_017911:4868262-4868516 [Pseudomonas fluorescens A506]
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFGGVGKPEPLKHNLSGFWSRRITAEHRLVYGIEDDEVQILMC
RYHY
MKILFTPEGWDDYLWFQQNDKAGLKRINLLIKAIQRDPFGGVGKPEPLKHNLSGFWSRRITAEHRLVYGIEDDEVQILMC
RYHY
Download Length: 255 bp
>T27836 NC_017911:4868262-4868516 [Pseudomonas fluorescens A506]
ATGAAAATACTCTTTACCCCTGAAGGCTGGGACGACTACCTCTGGTTTCAACAGAACGACAAAGCCGGGCTCAAGCGCAT
CAATCTCTTGATCAAGGCCATACAAAGAGACCCGTTCGGCGGCGTGGGGAAGCCTGAACCCCTCAAACATAACCTGAGTG
GTTTCTGGTCTCGACGAATCACCGCGGAGCATCGTTTGGTTTATGGCATCGAGGATGATGAAGTACAAATATTGATGTGC
CGCTACCACTACTGA
ATGAAAATACTCTTTACCCCTGAAGGCTGGGACGACTACCTCTGGTTTCAACAGAACGACAAAGCCGGGCTCAAGCGCAT
CAATCTCTTGATCAAGGCCATACAAAGAGACCCGTTCGGCGGCGTGGGGAAGCCTGAACCCCTCAAACATAACCTGAGTG
GTTTCTGGTCTCGACGAATCACCGCGGAGCATCGTTTGGTTTATGGCATCGAGGATGATGAAGTACAAATATTGATGTGC
CGCTACCACTACTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9576.93 Da Isoelectric Point: 7.2034
>AT27836 WP_003194039.1 NC_017911:4868011-4868265 [Pseudomonas fluorescens A506]
METINYTNARAHLSETMDRVNDDHVPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRR
LIEE
METINYTNARAHLSETMDRVNDDHVPLLLTRQKGEPVVMISLSEFNALEETAYLLRSPKNAERLINSVNSLRAGKAKPRR
LIEE
Download Length: 255 bp
>AT27836 NC_017911:4868011-4868265 [Pseudomonas fluorescens A506]
ATGGAAACTATCAACTACACCAACGCCCGAGCCCATCTGTCCGAAACGATGGACCGCGTCAATGATGATCACGTCCCACT
TCTACTGACTCGACAAAAAGGCGAGCCCGTGGTGATGATCTCGTTATCAGAGTTCAATGCTCTGGAAGAGACGGCTTACC
TGCTGCGCTCGCCTAAAAATGCCGAACGTCTCATTAACTCAGTCAACAGCTTACGAGCAGGCAAAGCCAAGCCAAGGCGG
TTGATTGAAGAATGA
ATGGAAACTATCAACTACACCAACGCCCGAGCCCATCTGTCCGAAACGATGGACCGCGTCAATGATGATCACGTCCCACT
TCTACTGACTCGACAAAAAGGCGAGCCCGTGGTGATGATCTCGTTATCAGAGTTCAATGCTCTGGAAGAGACGGCTTACC
TGCTGCGCTCGCCTAAAAATGCCGAACGTCTCATTAACTCAGTCAACAGCTTACGAGCAGGCAAAGCCAAGCCAAGGCGG
TTGATTGAAGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0W0MVT7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0W0MVN5 |