Detailed information of TA system TA027833

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 3598336..3598990
• Replicon: chromosome
• Accession: NC_017911
• Organism: Pseudomonas fluorescens A506

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: PFLA506_RS15910
• Protein ID: WP_014718914.1
• Coordinates: 3598336..3598686 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: A0A0W0N117
• Locus tag: PFLA506_RS15915
• Protein ID: WP_014718915.1
• Coordinates: 3598676..3598990 (+)
• Length: 105 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PFLA506_RS15900	3595094..3596626	+	1533	WP_014718913.1	NADH-quinone oxidoreductase subunit M	-
PFLA506_RS15905	3596634..3598097	+	1464	WP_003174731.1	NADH-quinone oxidoreductase subunit NuoN	-
PFLA506_RS15910	3598336..3598686	+	351	WP_014718914.1	hypothetical protein	Toxin
PFLA506_RS15915	3598676..3598990	+	315	WP_014718915.1	XRE family transcriptional regulator	Antitoxin
PFLA506_RS15920	3599048..3599800	-	753	WP_014718916.1	outer membrane beta-barrel protein	-
PFLA506_RS15925	3599926..3600759	-	834	WP_014718917.1	arylamine N-acetyltransferase	-
PFLA506_RS15930	3600880..3601116	+	237	WP_014718918.1	hypothetical protein	-
PFLA506_RS15935	3601147..3601341	-	195	WP_005789138.1	hypothetical protein	-
PFLA506_RS15940	3601354..3601533	-	180	WP_014718919.1	hypothetical protein	-
PFLA506_RS15945	3601648..3602169	+	522	WP_014718920.1	DUF3087 family protein	-
PFLA506_RS15950	3602178..3603059	-	882	WP_014718921.1	Dyp-type peroxidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13691.69 Da
• Isoelectric Point: 9.9912

>T27833 WP_014718914.1 NC_017911:3598336-3598686 [Pseudomonas fluorescens A506]
MDALFIELPAFERYRKDYLSDELYRGFQQELMKNPEAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYGWSGGTQFWL
FTLYGKHEQNDLAPQHKKALKHMLVREIKARMHNET

Nucleotide

• Length: 351 bp

>T27833 NC_017911:3598336-3598686 [Pseudomonas fluorescens A506]
ATGGATGCTCTATTTATCGAACTGCCGGCATTCGAGCGGTATCGCAAGGACTATCTGAGTGACGAGCTTTACCGCGGTTT
TCAACAGGAGTTGATGAAGAACCCCGAAGCGGGAGACGTGATCGAAGGAACGGGTGGGTTGAGAAAGGTTCGCTTCGTCG
ATGAGCGGCGAAACAAAGGCAAGCGCGGTGGCCTGCGGGTCATTTATTACGGGTGGTCAGGCGGTACGCAATTCTGGTTA
TTCACCTTGTACGGCAAACACGAACAAAACGACCTGGCACCGCAACACAAGAAAGCCCTTAAACACATGCTGGTCAGGGA
AATCAAAGCGAGAATGCACAATGAAACGTGA

Antitoxin

Protein

• Length: 105 a.a.
• Molecular weight: 11755.58 Da
• Isoelectric Point: 10.6525

>AT27833 WP_014718915.1 NC_017911:3598676-3598990 [Pseudomonas fluorescens A506]
MKRDIFSELVEGFDALADERQGKITLRNHKVHLNKLAPLTADEVIAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRAKPN
AQAVTLIRLVARFPETVAQLAALG

Nucleotide

• Length: 315 bp

>AT27833 NC_017911:3598676-3598990 [Pseudomonas fluorescens A506]
ATGAAACGTGACATCTTTTCCGAACTGGTCGAAGGCTTCGACGCTTTGGCCGATGAACGCCAGGGTAAAATCACCCTGCG
CAACCACAAAGTGCACCTCAACAAGCTGGCGCCGCTTACCGCAGACGAGGTGATCGCTGTGCGCCAGCAACTCAACCTCT
CCCGGTCGGTATTCGCCATGTATCTGCGTACCAACACCCGCACCCTGGAAAACTGGGAACAAGGCCGGGCCAAACCCAAC
GCCCAGGCCGTCACCCTGATCCGCCTGGTGGCGCGCTTTCCGGAAACCGTGGCGCAACTGGCCGCACTGGGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A0W0N117