Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | ralRA/- |
| Location | 2070526..2070897 | Replicon | chromosome |
| Accession | NZ_CP122923 | ||
| Organism | Escherichia coli strain ETEC1703 | ||
Toxin (Protein)
| Gene name | ralR | Uniprot ID | - |
| Locus tag | QDX14_RS10040 | Protein ID | WP_187182214.1 |
| Coordinates | 2070703..2070897 (-) | Length | 65 a.a. |
Antitoxin (RNA)
| Gene name | ralA | ||
| Locus tag | - | ||
| Coordinates | 2070526..2070704 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QDX14_RS10000 (2065968) | 2065968..2066624 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QDX14_RS10005 (2066726) | 2066726..2066956 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QDX14_RS10010 (2067095) | 2067095..2067469 | + | 375 | WP_000168747.1 | CopC domain-containing protein YobA | - |
| QDX14_RS10015 (2067473) | 2067473..2068345 | + | 873 | WP_000879295.1 | copper homeostasis membrane protein CopD | - |
| QDX14_RS10020 (2068358) | 2068358..2068699 | + | 342 | WP_000976472.1 | YebY family protein | - |
| QDX14_RS10025 (2069092) | 2069092..2070168 | - | 1077 | WP_053508942.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| QDX14_RS10030 (2070134) | 2070134..2070415 | - | 282 | WP_077248935.1 | excisionase | - |
| - (2070526) | 2070526..2070704 | + | 179 | NuclAT_1 | - | Antitoxin |
| - (2070526) | 2070526..2070704 | + | 179 | NuclAT_1 | - | Antitoxin |
| - (2070526) | 2070526..2070704 | + | 179 | NuclAT_1 | - | Antitoxin |
| - (2070526) | 2070526..2070704 | + | 179 | NuclAT_1 | - | Antitoxin |
| QDX14_RS10035 (2070522) | 2070522..2070710 | - | 189 | WP_021529595.1 | DUF1187 family protein | - |
| QDX14_RS10040 (2070703) | 2070703..2070897 | - | 195 | WP_187182214.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | Toxin |
| QDX14_RS10045 (2070961) | 2070961..2072049 | - | 1089 | WP_230905604.1 | RecT family recombinase | - |
| QDX14_RS10050 (2072064) | 2072064..2075201 | - | 3138 | WP_282863206.1 | PD-(D/E)XK nuclease-like domain-containing protein | - |
| QDX14_RS10055 (2075282) | 2075282..2075485 | - | 204 | WP_053289477.1 | DUF1482 family protein | - |
| QDX14_RS10060 (2075482) | 2075482..2075670 | - | 189 | WP_089565158.1 | cell division inhibition protein DicB | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2063226..2134919 | 71693 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 65 a.a. Molecular weight: 7032.96 Da Isoelectric Point: 9.2886
>T278212 WP_187182214.1 NZ_CP122923:c2070897-2070703 [Escherichia coli]
MRYEKVKPCPFCGCPSVTVKGISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
MRYEKVKPCPFCGCPSVTVKGISGYYRAKCNGCESRTGYGGSEKEALERWNKRTTGNNNGGVHV
Download Length: 195 bp
Antitoxin
Download Length: 179 bp
>AT278212 NZ_CP122923:2070526-2070704 [Escherichia coli]
GAGGGCAGAAGTTTCTCGCAATTAAAATTTATCAGCTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTCCCCGA
GAGCATTTTTTCGCATTCCGATTTGGTTAACTTTGTTTTTGAGTACCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
GAGGGCAGAAGTTTCTCGCAATTAAAATTTATCAGCTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTCCCCGA
GAGCATTTTTTCGCATTCCGATTTGGTTAACTTTGTTTTTGAGTACCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
