Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 3992134..3992675 Replicon chromosome
Accession NZ_CP122832
Organism Escherichia coli strain ETEC1730

Toxin (Protein)


Gene name yafQ Uniprot ID Q32JN3
Locus tag QDY27_RS20125 Protein ID WP_000615980.1
Coordinates 3992397..3992675 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag QDY27_RS20120 Protein ID WP_000729707.1
Coordinates 3992134..3992394 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDY27_RS20100 (3987901) 3987901..3988686 - 786 WP_000207556.1 putative lateral flagellar export/assembly protein LafU -
QDY27_RS20105 (3988658) 3988658..3990370 + 1713 Protein_3933 flagellar biosynthesis protein FlhA -
QDY27_RS20110 (3990502) 3990502..3990999 - 498 WP_000006245.1 REP-associated tyrosine transposase RayT -
QDY27_RS20115 (3991175) 3991175..3991948 - 774 WP_000543885.1 C40 family peptidase -
QDY27_RS20120 (3992134) 3992134..3992394 + 261 WP_000729707.1 type II toxin-antitoxin system antitoxin DinJ Antitoxin
QDY27_RS20125 (3992397) 3992397..3992675 + 279 WP_000615980.1 type II toxin-antitoxin system mRNA interferase toxin YafQ Toxin
QDY27_RS20130 (3992831) 3992831..3993571 + 741 WP_001225679.1 peptidoglycan meso-diaminopimelic acid protein amidase -
QDY27_RS20135 (3993542) 3993542..3994309 - 768 WP_000333380.1 class II glutamine amidotransferase -
QDY27_RS20140 (3994515) 3994515..3995093 - 579 WP_000284050.1 D-sedoheptulose 7-phosphate isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gmhA/lpcA 3951511..4019809 68298


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(5-92)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10830.62 Da        Isoelectric Point: 10.0702

>T278004 WP_000615980.1 NZ_CP122832:3992397-3992675 [Escherichia coli]
MIQRDIEYSGQFSKDVKLAQKRHKDMNKLKYLMTLLINNTLPLPAVYKDHPLQGSWKGYRDAHVEPDWLLIYKLTDKLLR
FERTGTHAALFG

Download         Length: 279 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9421.80 Da        Isoelectric Point: 5.0758

>AT278004 WP_000729707.1 NZ_CP122832:3992134-3992394 [Escherichia coli]
MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVAREKALPFDLREPNQLTIQSIKNSEAGVDVHKTKDADDL
FDKLGI

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A090NH48

Antitoxin

Source ID Structure

References