Detailed information of TA system TA027795

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): ldrD-ohsC/Ldr(toxin)
• Location: 4369384..4369605
• Replicon: chromosome
• Accession: NC_017906
• Organism: Escherichia coli Xuzhou21

Toxin (Protein)

• Gene name: ldrD
• Uniprot ID: S1NWX0
• Locus tag: CDCO157_RS31605
• Protein ID: WP_001295224.1
• Coordinates: 4369384..4369491 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	ohsC
Locus tag	-
Coordinates	4369540..4369605 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CDCO157_RS22540	4364637..4365389	-	753	Protein_4251	cellulose biosynthesis protein BcsQ	-
CDCO157_RS22550	4365401..4365589	-	189	WP_001063316.1	YhjR family protein	-
CDCO157_RS22555	4365862..4367433	+	1572	WP_001204920.1	cellulose biosynthesis protein BcsE	-
CDCO157_RS22560	4367430..4367621	+	192	WP_000988308.1	cellulose biosynthesis protein BcsF	-
CDCO157_RS22565	4367618..4369297	+	1680	WP_000191596.1	cellulose biosynthesis protein BcsG	-
CDCO157_RS31605	4369384..4369491	-	108	WP_001295224.1	type I toxin-antitoxin system toxin Ldr family protein	Toxin
-	4369540..4369605	+	66	NuclAT_15	-	Antitoxin
-	4369540..4369605	+	66	NuclAT_15	-	Antitoxin
-	4369540..4369605	+	66	NuclAT_15	-	Antitoxin
-	4369540..4369605	+	66	NuclAT_15	-	Antitoxin
-	4369540..4369605	+	66	NuclAT_20	-	Antitoxin
-	4369540..4369605	+	66	NuclAT_20	-	Antitoxin
-	4369540..4369605	+	66	NuclAT_20	-	Antitoxin
-	4369540..4369605	+	66	NuclAT_20	-	Antitoxin
CDCO157_RS22580	4369967..4371238	+	1272	WP_001301684.1	amino acid permease	-
CDCO157_RS22585	4371268..4372272	-	1005	WP_000107027.1	dipeptide ABC transporter ATP-binding subunit DppF	-
CDCO157_RS22590	4372269..4373252	-	984	WP_001196486.1	dipeptide ABC transporter ATP-binding protein	-
CDCO157_RS22595	4373263..4374165	-	903	WP_000084677.1	dipeptide ABC transporter permease DppC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Type I toxin-antitoxin system, toxin Ldr (1-35)

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 3882.70 Da
• Isoelectric Point: 9.0157

>T27795 WP_001295224.1 NC_017906:c4369491-4369384 [Escherichia coli Xuzhou21]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Nucleotide

• Length: 108 bp

>T27795 NC_017906:c4369491-4369384 [Escherichia coli Xuzhou21]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin

Nucleotide

• Length: 66 bp

>AT27795 NC_017906:4369540-4369605 [Escherichia coli Xuzhou21]
GTCTAGGTTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT

Structures

Toxin

• AlphaFold DB: A0A4P7TSJ7

Antitoxin