Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) symE-orzP/SymE(toxin)
Location 4854917..4855329 Replicon chromosome
Accession NZ_CP122768
Organism Escherichia coli strain ETEC1738

Toxin (Protein)


Gene name symE Uniprot ID -
Locus tag QDY55_RS24365 Protein ID WP_064225814.1
Coordinates 4854988..4855329 (+) Length 114 a.a.

Antitoxin (RNA)


Gene name orzP
Locus tag -
Coordinates 4854917..4854993 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDY55_RS24350 (4851806) 4851806..4853395 + 1590 WP_064225816.1 type I restriction-modification system methyltransferase -
QDY55_RS24355 (4853392) 4853392..4854072 + 681 WP_187771894.1 restriction endonuclease subunit S -
QDY55_RS24360 (4854399) 4854399..4854760 + 362 Protein_4777 restriction endonuclease subunit S -
- (4854917) 4854917..4854993 - 77 NuclAT_11 - Antitoxin
- (4854917) 4854917..4854993 - 77 NuclAT_11 - Antitoxin
- (4854917) 4854917..4854993 - 77 NuclAT_11 - Antitoxin
- (4854917) 4854917..4854993 - 77 NuclAT_11 - Antitoxin
- (4854917) 4854917..4854993 - 77 NuclAT_12 - Antitoxin
- (4854917) 4854917..4854993 - 77 NuclAT_12 - Antitoxin
- (4854917) 4854917..4854993 - 77 NuclAT_12 - Antitoxin
- (4854917) 4854917..4854993 - 77 NuclAT_12 - Antitoxin
QDY55_RS24365 (4854988) 4854988..4855329 + 342 WP_064225814.1 endoribonuclease SymE Toxin
QDY55_RS24370 (4855491) 4855491..4856870 + 1380 WP_064225813.1 5-methylcytosine-specific restriction endonuclease subunit McrB -
QDY55_RS24375 (4856870) 4856870..4857916 + 1047 WP_074397940.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - espX6 4854012..4878639 24627


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SymE-like

(20-71)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12275.12 Da        Isoelectric Point: 8.4888

>T277878 WP_064225814.1 NZ_CP122768:4854988-4855329 [Escherichia coli]
MTDTNFIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTAVDVKVMEGCIVLTAQPPAAEESE
LMQSLRQVCKLSARKQKQVQAFIGVIAGKQKVA

Download         Length: 342 bp

Antitoxin


Download         Length: 77 bp

>AT277878 NZ_CP122768:c4854993-4854917 [Escherichia coli]
AGTCATAACTGCTATTCTCCTGGAATAGTGATTGTGATGAGCGGTGCGGGTGTGTTGGCGCACATCCGCACCGCGCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References