Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/COG4683-HTH_37
Location 29473..29975 Replicon chromosome
Accession NZ_CP122565
Organism Auritidibacter ignavus strain BABAE-5

Toxin (Protein)


Gene name HigB2 Uniprot ID -
Locus tag QDX23_RS00150 Protein ID WP_233487799.1
Coordinates 29473..29664 (+) Length 64 a.a.

Antitoxin (Protein)


Gene name HigA2 Uniprot ID -
Locus tag QDX23_RS00155 Protein ID WP_110100392.1
Coordinates 29670..29975 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX23_RS00125 (QDX23_00125) 25500..26585 + 1086 WP_110100193.1 redox-regulated ATPase YchF -
QDX23_RS00130 (QDX23_00130) 26733..26966 + 234 WP_110100006.1 Arc family DNA-binding protein -
QDX23_RS00135 (QDX23_00135) 26963..27388 + 426 WP_110100194.1 type II toxin-antitoxin system VapC family toxin -
QDX23_RS00140 (QDX23_00140) 27401..27937 + 537 WP_158524689.1 GNAT family N-acetyltransferase -
QDX23_RS00145 (QDX23_00145) 28481..29206 + 726 WP_110100197.1 hypothetical protein -
QDX23_RS00150 (QDX23_00150) 29473..29664 + 192 WP_233487799.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QDX23_RS00155 (QDX23_00155) 29670..29975 + 306 WP_110100392.1 helix-turn-helix transcriptional regulator Antitoxin
QDX23_RS00160 (QDX23_00160) 30344..30718 + 375 WP_146206389.1 hypothetical protein -
QDX23_RS00165 (QDX23_00165) 30984..31748 + 765 WP_110100200.1 sulfite exporter TauE/SafE family protein -
QDX23_RS00170 (QDX23_00170) 32491..32721 - 231 WP_147472552.1 hypothetical protein -
QDX23_RS00175 (QDX23_00175) 32791..33546 + 756 WP_246840110.1 sulfite exporter TauE/SafE family protein -
QDX23_RS00180 (QDX23_00180) 33690..34061 + 372 WP_146206390.1 hypothetical protein -
QDX23_RS00185 (QDX23_00185) 34303..34689 + 387 WP_110100203.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(1-53)

Antitoxin

Cro/C1-type helix-turn-helix domain

(34-88)


Sequences

Toxin        


Download         Length: 64 a.a.        Molecular weight: 7512.68 Da        Isoelectric Point: 8.6796

>T277174 WP_233487799.1 NZ_CP122565:29473-29664 [Auritidibacter ignavus]
MKELRPGSSGRSELRVLFAFDPERVAIMLIAEDKIGDWKRWYKKHISLADDLFDEHLARLRRE

Download         Length: 192 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11378.08 Da        Isoelectric Point: 9.9101

>AT277174 WP_110100392.1 NZ_CP122565:29670-29975 [Auritidibacter ignavus]
MPKNLKDFVAEHPVDRGRVEAHKKRMLAEVRAYRLRELREQAGLTQAQLAERIGVGQRQVSKIEQGDLDSAKVGTIRSYL
EAVGGELSLEYVMGDQRMKVA

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References