Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 3969811..3970466 Replicon chromosome
Accession NZ_CP122540
Organism Pseudomonas brenneri strain K5-sn1400

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag QDY63_RS18460 Protein ID WP_032857392.1
Coordinates 3969811..3970155 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A5B2UU43
Locus tag QDY63_RS18465 Protein ID WP_032857393.1
Coordinates 3970152..3970466 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDY63_RS18450 (QDY63_18450) 3966569..3968101 + 1533 WP_029293337.1 NADH-quinone oxidoreductase subunit M -
QDY63_RS18455 (QDY63_18455) 3968109..3969572 + 1464 WP_029293335.1 NADH-quinone oxidoreductase subunit NuoN -
QDY63_RS18460 (QDY63_18460) 3969811..3970155 + 345 WP_032857392.1 toxin Toxin
QDY63_RS18465 (QDY63_18465) 3970152..3970466 + 315 WP_032857393.1 transcriptional regulator Antitoxin
QDY63_RS18470 (QDY63_18470) 3970553..3972295 - 1743 WP_032857394.1 ABC transporter substrate-binding protein -
QDY63_RS18475 (QDY63_18475) 3972462..3972734 - 273 WP_029293327.1 DUF2160 domain-containing protein -
QDY63_RS18480 (QDY63_18480) 3972745..3973545 - 801 WP_032857395.1 carbohydrate ABC transporter permease -
QDY63_RS18485 (QDY63_18485) 3973556..3974422 - 867 WP_032857398.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13511.52 Da        Isoelectric Point: 10.0671

>T277167 WP_032857392.1 NZ_CP122540:3969811-3970155 [Pseudomonas brenneri]
MDALFIELPPFERYRKDYLTDELFHGFQQELMKNPEAGAVMEGTGGLRKLRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQSDLSPQHKKALKHMLDREIKARGFT

Download         Length: 345 bp

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11820.56 Da        Isoelectric Point: 10.5761

>AT277167 WP_032857393.1 NZ_CP122540:3970152-3970466 [Pseudomonas brenneri]
MNRDIFSELVEGFDALANERQGKVTLRTHTVQQNKLAPLTAEDVIAVRQQLNLSRAVFAMYLRTNTRTLENWEQGRARPN
AQAAILIRLVSKFPDTVERLALLS

Download         Length: 315 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5B2UU43

References